Microbial genetics - Hypermutation under stress

被引:45
作者
Bridges, BA
机构
[1] MRC Cell Mutation Unit,
[2] University of Sussex,undefined
关键词
D O I
10.1038/42370
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
When microorganisms are starved of nutrients, the rate of mutation of their genomes accelerates. But are these mutations directed towards those genes that might prove effective in rectifying the nutritional deficiency concerned, or are they random? New studies on a commonly used system (mutants of Escherichia coli that cannot use lactose) point to the second possibility.
引用
收藏
页码:557 / 558
页数:2
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