Pushing back the limits of electron cryomicroscopy

被引：16

作者：

Chiu, W ^{[1
]}

Schmid, MF ^{[1
]}

机构：

[1] BAYLOR COLL MED,VERNA & MARRS MCLEAN DEPT BIOCHEM,HOUSTON,TX 77030

来源：

NATURE STRUCTURAL BIOLOGY | 1997年 / 4卷 / 05期

关键词：

D O I：

10.1038/nsb0597-331

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A convergence of technical advances in electron cryomicroscopy will allow visualization of biomolecular assemblies, without crystals, at resolutions below 10 Å. Recent cryomicroscopic structures of papillomavirus and hepatitis B virus capsid provide case studies.

引用

页码：331 / 333

页数：3

共 44 条

[1] Direct visualization of A-, P-, and E-site transfer RNAs in the Escherichia coli ribosome [J].

Agrawal, RK ;

Penczek, P ;

Grassucci, RA ;

Li, YH ;

Leith, A ;

Nierhaus, KH ;

Frank, J .

SCIENCE, 1996, 271 (5251) :1000-1002

[2] STRUCTURAL PLASTICITY OF THE NUCLEAR-PORE COMPLEX [J].

AKEY, CW .

JOURNAL OF MOLECULAR BIOLOGY, 1995, 248 (02) :273-293

[3] Visualization of beta-sheets and side-chain clusters in two-dimensional periodic arrays of streptavidin on phospholipid monolayers by electron crystallography [J].

AvilaSakar, AJ ;

Chiu, W .

BIOPHYSICAL JOURNAL, 1996, 70 (01) :57-68

[4]

BAKER JS, 1997, STRUCTURAL BIOL VIRU, P38

[5] A model-based approach for determining orientations of biological macromolecules imaged by cryoelectron microscopy [J].

Baker, TS ;

Cheng, RH .

JOURNAL OF STRUCTURAL BIOLOGY, 1996, 116 (01) :120-130

[6] Determination of the fold of the core protein of hepatitis B virus ky electron cryomicroscopy [J].

Bottcher, B ;

Wynne, SA ;

Crowther, RA .

NATURE, 1997, 386 (6620) :88-91

[7] Visualization of a 4-helix bundle in the hepatitis B virus capsid by cryo-electron microscopy [J].

Conway, JF ;

Cheng, N ;

Zlotnick, A ;

Wingfield, PT ;

Stahl, SJ ;

Steven, AC .

NATURE, 1997, 386 (6620) :91-94

[8] PROCEDURES FOR 3-DIMENSIONAL RECONSTRUCTION OF SPHERICAL VIRUSES BY FOURIER SYNTHESIS FROM ELECTRON MICROGRAPHS [J].

CROWTHER, RA .

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, 1971, 261 (837) :221-+

[9] RECONSTRUCTION OF 3 DIMENSIONAL STRUCTURES FROM ELECTRON MICROGRAPHS [J].

DEROSIER, DJ ;

KLUG, A .

NATURE, 1968, 217 (5124) :130-&

[10] SPOT-SCAN IMAGING IN TRANSMISSION ELECTRON-MICROSCOPY [J].

DOWNING, KH .

SCIENCE, 1991, 251 (4989) :53-59

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