Effects of multiple-passage probabilities on fluorescent signals from biological media

被引：23

作者：

Gandjbakhche, AH ^{[1
]}

Bonner, RF ^{[1
]}

Nossal, R ^{[1
]}

Weiss, GH ^{[1
]}

机构：

[1] NIH,NATL CTR RES RESOURCES,BIOMED ENGN & INSTRUMENTAT PROGRAM,BETHESDA,MD 20892

来源：

APPLIED OPTICS | 1997年 / 36卷 / 19期

关键词：

D O I：

10.1364/AO.36.004613

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

By applying a random-walk model for photon migration, we find an exact expression for fluorescent signals emitted from a homogeneous, optically turbid medium containing a single fluorescent mass. In contrast to diffusion-theory-based models, our analysis accounts for multiple photon passages through the fluorophore sites and allows for a variable degree of fluorescent absorptivity. We particularly discuss effects on the amplitudes and phase shifts of frequency-domain fluorescent signals. (C) 1997 Optical Society of America.

引用

页码：4613 / 4619

页数：9

共 16 条

[11] MATHEMATICAL-MODEL FOR TIME-RESOLVED AND FREQUENCY-DOMAIN FLUORESCENCE SPECTROSCOPY IN BIOLOGICAL TISSUE [J].

PATTERSON, MS ;

POGUE, BW .

APPLIED OPTICS, 1994, 33 (10) :1963-1974

[12] TIME-DEPENDENT PHOTON MIGRATION USING PATH-INTEGRALS [J].

PERELMAN, LT ;

WU, J ;

WANG, Y ;

ITZKAN, I ;

DASARI, RR ;

FELD, MS .

PHYSICAL REVIEW E, 1995, 51 (06) :6134-6141

[13] FORMAT PHOTONS IN TURBID MEDIA - AN EXACT ANALYTIC SOLUTION FOR MOST FAVORABLE PATHS - A STEP TOWARD OPTICAL TOMOGRAPHY [J].

POLISHCHUK, AY ;

ALFANO, RR .

OPTICS LETTERS, 1995, 20 (19) :1937-1939

[14] RANDOM-WALKS ON LATTICES - THE PROBLEM OF VISITS TO A SET OF POINTS REVISITED [J].

RUBIN, RJ ;

WEISS, GH .

JOURNAL OF MATHEMATICAL PHYSICS, 1982, 23 (02) :250-253

[15]

SEVICKMURACA EM, 1995, P SOC PHOTO-OPT INS, V2387, P62, DOI 10.1117/12.206805

[16]

Weiss G.H., 1994, Aspects and Applications of the Random Walk

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