Reaching a genetic and molecular understanding of skeletal development

被引:1217
作者
Karsenty, G [1 ]
Wagner, EF
机构
[1] Baylor Coll Med, Dept Mol & Human Genet, Houston, TX 77030 USA
[2] Res Inst Mol Pathol, IMP, A-1030 Vienna, Austria
基金
美国国家卫生研究院;
关键词
D O I
10.1016/S1534-5807(02)00157-0
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
In the last ten years, we have made considerable progress in our genetic and molecular understanding of all aspects of skeletal development, chondrogenesis, joint formation, and osteogenesis. This review addresses the role of the principal growth factors and transcription factors affecting these different processes and presents, in several cases, the genetic cascade leading to cell differentiation.
引用
收藏
页码:389 / 406
页数:18
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