The topical protective effect of soybean-germ oil against UVB-induced cutaneous erythema:: an in vivo evaluation

被引：19

作者：

Bonina, F

Puglia, C

Avogadro, M

Baranelli, E

Cravotto, G

机构：

[1] Univ Turin, Dipartimento Sci & Tecnol Farmaco, I-10125 Turin, Italy

[2] Catania Univ, Dipartimento Sci Farmaceut, Catania, Italy

来源：

ARCHIV DER PHARMAZIE | 2005年 / 338卷 / 12期

关键词：

soybean-germ oil; analysis; erythema; tocopherol acetate; antioxidant;

D O I：

10.1002/ardp.200500159

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The preparation and detailed composition of an oil newly extracted from pure soy germ (not less than 96% hypocotyle) are presented. Experiments in vivo showed that soybean-germ oil (SGO) possesses a remarkable protective activity against UVB-induced skin inflammation, exceeding that of tocopberol acetate by a factor of 2. These results suggest that SGO might have interesting therapeutic and cosmetic applications in the management of skin diseases initiated, sustained, or exacerbated by an overproduction of free radicals.

引用

页码：598 / 601

页数：4

共 21 条

[11] Nitric oxide produced by ultraviolet-irradiated keratinocytes stimulates melanogenesis [J].