Evolution of human endogenous retroviral sequences: a conceptual account

被引：85

作者：

Blikstad, V. ^{[1
]}

Benachenhou, F. ^{[1
]}

Sperber, G. O. ^{[2
]}

Blomberg, J. ^{[1
]}

机构：

[1] Uppsala Univ, Acad Hosp, Dept Med Sci, Virol Sect, S-75185 Uppsala, Sweden

[2] Uppsala Univ, Dept Neurosci Physiol, Uppsala, Sweden

来源：

CELLULAR AND MOLECULAR LIFE SCIENCES | 2008年 / 65卷 / 21期

关键词：

Endogenous retrovirus; evolution; lateral transfer; virulence; vertebrate genome; bioinformatics; sequence recognition;

D O I：

10.1007/s00018-008-8495-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Endogenous retroviruses (ERVs) most likely are remnants of ancient retroviral infections. ERVs preserve functions of exogenous retroviruses to a varying extent, and can be parasites, symbionts or more or less neutral genetic 'junk'.Their evolution has two facets, pre- and post-endogenization. Although the two are not clearly separated, the first pertains to retroviral evolution in general and the second to the fate of repetitive DNA and the evolution of the host organism and its genome. The study of ERVs provides much material for the understanding of retroviral evolution. This sequence archive reflects the history of successes and shortcomings of antiviral resistance, but also of strategic evolutionary decisions regarding genome organization and new gene acquisition. This review discusses retroviral evolution illustrated through HERVs, bioinformatic prerequisites for ERV studies, the endogenization process and HERV evolution post-endogenization, including relation to disease. (Part of a Multi-author Review).

引用

页码：3348 / 3365

页数：18

共 184 条

[1]

ABRAMCZUK JW, 1992, J ACQ IMMUN DEF SYND, V5, P196

[2] Comparative expression of human endogenous retrovirus-W genes in multiple sclerosis [J].

Antony, Joseph M. ;

Zhu, Yu ;

Izad, Maryam ;

Warren, Kenneth G. ;

Vodjgani, Mohammed ;

Mallet, Francois ;

Power, Christopher .

AIDS RESEARCH AND HUMAN RETROVIRUSES, 2007, 23 (10) :1251-1256

[3] The Piwi-piRNA pathway provides an adaptive defense in the transposon arms race [J].

Aravin, Alexei A. ;

Hannon, Gregory J. ;

Brennecke, Julius .

SCIENCE, 2007, 318 (5851) :761-764

[4] Mechanisms of late restriction induced by an endogenous retrovirus [J].

Arnaud, Frederick ;

Murcia, Pablo R. ;

Palmarini, Massimo .

JOURNAL OF VIROLOGY, 2007, 81 (20) :11441-11451

[5] Transcripts from a novel human KRAB zinc finger gene contain spliced Alu and endogenous retroviral segments [J].

Baban, S ;

Freeman, JD ;

Mager, DL .

GENOMICS, 1996, 33 (03) :463-472

[6] Hybrid origin of SIV in chimpanzees [J].

Bailes, E ;

Gao, F ;

Bibollet-Ruche, F ;

Courgnaud, V ;

Peeters, M ;

Marx, PA ;

Hahn, BH ;

Sharp, PM .

SCIENCE, 2003, 300 (5626) :1713-1713

[7] Many human endogenous retrovirus K (HERV-K) proviruses are unique to humans [J].

Barbulescu, M ;

Turner, G ;

Seaman, MI ;

Deinard, AS ;

Kidd, KK ;

Lenz, J .

CURRENT BIOLOGY, 1999, 9 (16) :861-868

[8] Integration targeting by avian sarcoma-leukosis virus and human immunodeficiency virus in the chicken genome [J].

Barr, SD ;

Leipzig, J ;

Shinn, P ;

Ecker, JR ;

Bushman, FD .

JOURNAL OF VIROLOGY, 2005, 79 (18) :12035-12044

[9] ISOLATION OF A T-LYMPHOTROPIC RETROVIRUS FROM A PATIENT AT RISK FOR ACQUIRED IMMUNE-DEFICIENCY SYNDROME (AIDS) [J].

BARRESINOUSSI, F ;

CHERMANN, JC ;

REY, F ;

NUGEYRE, MT ;

CHAMARET, S ;

GRUEST, J ;

DAUGUET, C ;

AXLERBLIN, C ;

VEZINETBRUN, F ;

ROUZIOUX, C ;

ROZENBAUM, W ;

MONTAGNIER, L .

SCIENCE, 1983, 220 (4599) :868-871

[10] Intracellular restriction factors in mammalian cells - An ancient defense system finds a modern foe [J].

Baumann, JG .

CURRENT HIV RESEARCH, 2006, 4 (02) :141-168

← 1 2 3 4 5 6 7 8 9 10 →