Molecular imprinted polymers: Useful tools for pharmaceutical analysis

被引:20
作者
Baggiani, Claudio [1 ]
Anfossi, Laura [1 ]
Giovannoli, Cristina [1 ]
机构
[1] Univ Turin, Dipartimento Chim Analit, I-10125 Turin, Italy
关键词
molecular imprinting; chiral separation; solid phase extraction; libraries; high throughput screening; capillary electrochromatography; capillary electrophoresis;
D O I
10.2174/157341206777934662
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Molecular imprinted polymers are man-made materials with predetermined selectivity towards one or more analytes. They have been used as selective stationary phases in several analytical separative techniques. This review discusses the possible uses of imprinted polymers, with a particular emphasis on their use as high pressure and electrochromatographic stationary phases for resolution of optical enantiomers, materials for fast screening of libraries and selective solid-phase extraction for sample clean-up and preconcentration.
引用
收藏
页码:219 / 247
页数:29
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