How does TAP associate with MHC class I molecules?

被引：58

作者：

Elliott, T

机构：

来源：

IMMUNOLOGY TODAY | 1997年 / 18卷 / 08期

基金：

英国惠康基金;

关键词：

D O I：

10.1016/S0167-5699(97)01097-9

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Major histocompatibility complex (MHC) class I molecules in the endoplasmic reticulum (ER) are in physical association with a number of cofactors, including the transporter associated with antigen processing (TAP) and a calcium-binding chaperone. Here, Tim Elliott suggests a molecular model for the way in which these cofactors could regulate the assembly and release of newly synthesized MHC class I molecules.

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收藏

页码：375 / 379

页数：5

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