Natural Antimicrobials ε-Poly-L-lysine and Nisin A for Control of Oral Microflora

被引:38
作者
Najjar, Mohamed Badaoui [1 ]
Kashtanov, Dimitri [1 ]
Chikindas, Michael L. [1 ]
机构
[1] Rutgers State Univ, Dept Food Sci, New Brunswick, NJ 08901 USA
关键词
Nisin; Poly-lysine; Oral microflora; Synergy; Antimicrobial; IN-VITRO; PEPTIDE NISIN; EFFICACY; SAFE;
D O I
10.1007/s12602-009-9020-0
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
The present study aims to examine the efficacy of the natural antimicrobial epsilon-poly-L-lysine against Streptococcus mutans and against total aerobic oral microflora, alone and in combination with the natural antimicrobial peptide nisin. In in vitro studies, natural antimicrobials nisin A and epsilon-poly-L-lysine synergized in their action against S. mutans, leading to the microorganism's full inhibition, while having a less inhibitory effect on total aerobic oral microbiota.
引用
收藏
页码:143 / 147
页数:5
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