Is REST required for ESC pluripotency?

被引：48

作者：

Jorgensen, Helle F. ^{[1
]}

Chen, Zhou-Feng ^{[2
,3
]}

Merkenschlager, Matthias ^{[1
]}

Fisher, Amanda G. ^{[1
]}

机构：

[1] Imperial Coll Sch Med, MRC Clin Sci Ctr, Lymphocyte Dev Grp, London W12 0NN, England

[2] Washington Univ, Sch Med, Pain Ctr, Dept Anesthesiol, St Louis, MO 63110 USA

[3] Washington Univ, Sch Med, Pain Ctr, Dept Psychiat & Dev Biol, St Louis, MO 63110 USA

来源：

NATURE | 2009年 / 457卷 / 7233期

基金：

英国医学研究理事会;

关键词：

EMBRYONIC STEM-CELLS; SELF-RENEWAL; NETWORK; GENES;

D O I：

10.1038/nature07783

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Arising from: S. K. Singh, M. N. Kagalwala, J. Parker-Thornburg, H. Adams & S. Majumder Nature453, 223–227 (2008)10.1038/nature06863; Singh et al.reply

引用

页码：E4 / E5

页数：2

共 13 条

[1] Chromatin signatures of pluripotent cell lines [J].

Azuara, V ;

Perry, P ;

Sauer, S ;

Spivakov, M ;

Jorgensen, HF ;

John, RM ;

Gouti, M ;

Casanova, M ;

Warnes, G ;

Merkenschlager, M ;

Fisher, AG .

NATURE CELL BIOLOGY, 2006, 8 (05) :532-U189

[2] Normal timing of oligodendrocyte development from genetically engineered, lineage-selectable mouse ES cells [J].

Billon, N ;

Jolicoeur, C ;

Ying, QL ;

Smith, A ;

Raff, M .

JOURNAL OF CELL SCIENCE, 2002, 115 (18) :3657-3665

[3] Core transcriptional regulatory circuitry in human embryonic stem cells [J].

Boyer, LA ;

Lee, TI ;

Cole, MF ;

Johnstone, SE ;

Levine, SS ;

Zucker, JR ;

Guenther, MG ;

Kumar, RM ;

Murray, HL ;

Jenner, RG ;

Gifford, DK ;

Melton, DA ;

Jaenisch, R ;

Young, RA .

CELL, 2005, 122 (06) :947-956

[4] NRSF/REST is required in vivo for repression of multiple neuronal target genes during embryogenesis [J].

Chen, ZF ;

Paquette, AJ ;

Anderson, DJ .

NATURE GENETICS, 1998, 20 (02) :136-142

[5] TWIST IS REQUIRED IN HEAD MESENCHYME FOR CRANIAL NEURAL-TUBE MORPHOGENESIS [J].

CHEN, ZF ;

BEHRINGER, RR .

GENES & DEVELOPMENT, 1995, 9 (06) :686-699

[6] REST - A MAMMALIAN SILENCER PROTEIN THAT RESTRICTS SODIUM-CHANNEL GENE-EXPRESSION TO NEURONS [J].

CHONG, JHA ;

TAPIARAMIREZ, J ;

KIM, S ;

TOLEDOARAL, JJ ;

ZHENG, YC ;

BOUTROS, MC ;

ALTSHULLER, YM ;

FROHMAN, MA ;

KRANER, SD ;

MANDEL, G .

CELL, 1995, 80 (06) :949-957

[7] Niche-independent symmetrical self-renewal of a mammalian tissue stem cell [J].

Conti, L ;

Pollard, SM ;

Gorba, T ;

Reitano, E ;

Toselli, M ;

Biella, G ;

Sun, YR ;

Sanzone, S ;

Ying, QL ;

Cattaneo, E ;

Smith, A .

PLOS BIOLOGY, 2005, 3 (09) :1594-1606

[8] The impact of chromatin modifiers on the timing of locus replication in mouse embryonic stem cells [J].

Jorgensen, Helle F. ;

Azuara, Veronique ;

Amoils, Shannon ;

Spivakov, Mikhail ;

Terry, Anna ;

Nesterova, Tatyana ;

Cobb, Bradley S. ;

Ramsahoye, Bernard ;

Merkenschlager, Matthias ;

Fisher, Amanda G. .

GENOME BIOLOGY, 2007, 8 (08)

[9] An extended transcriptional network for pluripotency of embryonic stem cells [J].

Kim, Jonghwan ;

Chu, Jianlin ;

Shen, Xiaohua ;

Wang, Jianlong ;

Orkin, Stuart H. .

CELL, 2008, 132 (06) :1049-1061

[10] The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells [J].

Loh, YH ;

Wu, Q ;

Chew, JL ;

Vega, VB ;

Zhang, WW ;

Chen, X ;

Bourque, G ;

George, J ;

Leong, B ;

Liu, J ;

Wong, KY ;

Sung, KW ;

Lee, CWH ;

Zhao, XD ;

Chiu, KP ;

Lipovich, L ;

Kuznetsov, VA ;

Robson, P ;

Stanton, LW ;

Wei, CL ;

Ruan, YJ ;

Lim, B ;

Ng, HH .

NATURE GENETICS, 2006, 38 (04) :431-440

← 1 2 →