Gene silencing: RNA makes RNA makes no protein

被引：73

作者：

Baulcombe, DC ^{[1
]}

机构：

[1] John Innes Ctr, Sainsbury Lab, Norwich NR4 7UH, Norfolk, England

来源：

CURRENT BIOLOGY | 1999年 / 9卷 / 16期

关键词：

D O I：

10.1016/S0960-9822(99)80383-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A mutation that disrupts post-transcriptional gene silencing in Neurospora crassa has been found to affect the homologue of a plant-encoded RNA-dependent RNA polymerase. This enzyme may produce a specificity determinant of gene silencing and mediate an epigenetic conversion at the RNA level.

引用

页码：R599 / R601

页数：3

共 12 条

[11] Isolation of an RNA-Directed RNA polymerase-specific cDNA clone from tomato [J].

Schiebel, W ;

Pélissier, T ;

Riedel, L ;

Thalmeir, S ;

Schiebel, R ;

Kempe, D ;

Lottspeich, F ;

Sänger, HL ;

Wassenegger, M .

PLANT CELL, 1998, 10 (12) :2087-2101

[12] Virus resistance and gene silencing in plants can be induced by simultaneous expression of sense and antisense RNA [J].

Waterhouse, PM ;

Graham, HW ;

Wang, MB .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (23) :13959-13964

← 1 2 →