A crumpled surface having transverse attractive interactions as a simplified model with biological significance

被引:11
作者
Cassia-Moura, R
Gomes, MAF
机构
[1] Univ Fed Pernambuco, Inst Ciencias Biol, DCF, Dept Fis, BR-5067000 Recife, PE, Brazil
[2] Abdus Salaam Int Ctr Theoret Phys, I-34100 Trieste, Italy
关键词
crumpled surface; fractal dimension; membrane model; protein folding; short-range attractive force;
D O I
10.1016/j.jtbi.2005.05.015
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Using extensive analogical simulations with square sheets of paper we investigate the influence of short-range transverse attractive interactions on the packing properties of a crumpled Surface. These interactions are due to transverse connections or local bridges associated with a given number of binding sites localized on the two-dimensional surface and distributed in several patterns in the three-dimensional physical space. Geometrical relations and critical exponents describing the statistical properties of the crumpled surface are obtained as a function of the strength of the attractive interactions. Our model suggests how the presence of short-range interactions as, e.g. van der Waals forces can be important for the geometric plasticity of biological molecules, which in turn is important for biological function. The relevance of our results to the study of molecular conformation of proteins and membranes is discussed, and a comparison is also made between the behavior of the crumpled surface studied here and other important nonequilibrium fractal structures. (c) 2005 Elsevier Ltd. All rights reserved.
引用
收藏
页码:331 / 339
页数:9
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