NEURAL PROCESSING OF ITCH

被引：187

作者：

Akiyama, Tasuku ^{[1
]}

Carstens, E. ^{[1
]}

机构：

[1] Univ Calif Davis, Dept Neurobiol Physiol & Behav, Davis, CA 95616 USA

来源：

NEUROSCIENCE | 2013年 / 250卷

基金：

美国国家卫生研究院;

关键词：

itch; pruritus; spinal cord; trigeminal caudalis; scratching behavior; pruritogens; GASTRIN-RELEASING-PEPTIDE; SPINOTHALAMIC TRACT NEURONS; SUPERFICIAL DORSAL-HORN; RAT SPINAL-CORD; PROTEASE-ACTIVATED RECEPTORS; INDUCED SCRATCHING BEHAVIOR; STATE-DEPENDENT INHIBITION; ATOPIC-DERMATITIS PATIENTS; PRIMARY SENSORY NEURONS; ROOT GANGLION NEURONS;

D O I：

10.1016/j.neuroscience.2013.07.035

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

While considerable effort has been made to investigate the neural mechanisms of pain, much less effort has been devoted to itch, at least until recently. However, itch is now gaining increasing recognition as a widespread and costly medical and socioeconomic issue. This is accompanied by increasing interest in the underlying neural mechanisms of itch, which has become a vibrant and rapidly-advancing field of research. The goal of the present forefront review is to describe the recent progress that has been made in our understanding of itch mechanisms. (C) 2013 IBRO. Published by Elsevier Ltd. All rights reserved.

引用

页码：697 / 714

页数：18

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