Molecular control of nitric oxide synthases in the cardiovascular system

被引：147

作者：

Papapetropoulos, A ^{[1
]}

Rudic, RD ^{[1
]}

Sessa, WC ^{[1
]}

机构：

[1] Yale Univ, Sch Med, Boyer Ctr Mol Med, Dept Pharmacol,Mol Cardiobiol Program, New Haven, CT 06536 USA

来源：

CARDIOVASCULAR RESEARCH | 1999年 / 43卷 / 03期

关键词：

nitric oxide synthases; molecular control; cardiovascular system;

D O I：

10.1016/S0008-6363(99)00161-3

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Nitric oxide plays an important role in cardiovascular homeostasis. In this review, the regulation of the three nitric oxide synthase isoforms in the cardiovascular system are examined at molecular and cellular levels. In addition, recent information gleaned from the use of NOS knockout mice are discussed. (C) 1999 Elsevier Science B.V. All rights reserved.

引用

页码：509 / 520

页数：12

共 131 条

[1] NG-METHYLARGININE, AN INHIBITOR OF ENDOTHELIUM-DERIVED NITRIC-OXIDE SYNTHESIS, IS A POTENT PRESSOR AGENT IN THE GUINEA-PIG - DOES NITRIC-OXIDE REGULATE BLOOD-PRESSURE INVIVO [J].

AISAKA, K ;

GROSS, SS ;

GRIFFITH, OW ;

LEVI, R .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1989, 160 (02) :881-886

[2] Endothelial cytosolic proteins bind to the 3' untranslated region of endothelial nitric oxide synthase mRNA: Regulation by tumor necrosis factor alpha [J].

Alonso, J ;

deMiguel, LS ;

Monton, M ;

Casado, S ;

LopezFarre, A .

MOLECULAR AND CELLULAR BIOLOGY, 1997, 17 (10) :5719-5726

[3] CONTROL OF CARDIAC-MUSCLE CELL-FUNCTION BY AN ENDOGENOUS NITRIC-OXIDE SIGNALING SYSTEM [J].

BALLIGAND, JL ;

KELLY, RA ;

MARSDEN, PA ;

SMITH, TW ;

MICHEL, T .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1993, 90 (01) :347-351

[4] Neuronal nitric oxide synthase is expressed in rat vascular smooth muscle cells -: Activation by angiotensin II in hypertension [J].

Boulanger, CM ;

Heymes, C ;

Benessiano, J ;

Geske, RS ;

Lévy, BI ;

Vanhoutte, PM .

CIRCULATION RESEARCH, 1998, 83 (12) :1271-1278

[5]

BREDT DS, 1992, J BIOL CHEM, V267, P10976

[6] CLONED AND EXPRESSED NITRIC-OXIDE SYNTHASE STRUCTURALLY RESEMBLES CYTOCHROME-P-450 REDUCTASE [J].

BREDT, DS ;

HWANG, PM ;

GLATT, CE ;

LOWENSTEIN, C ;

REED, RR ;

SNYDER, SH .

NATURE, 1991, 351 (6329) :714-718

[7] Interaction of nitric oxide synthase with the postsynaptic density protein PSD-95 and alpha 1-syntrophin mediated by PDZ domains [J].

Brenman, JE ;

Chao, DS ;

Gee, SH ;

McGee, AW ;

Craven, SE ;

Santillano, DR ;

Wu, ZQ ;

Huang, F ;

Xia, HH ;

Peters, MF ;

Froehner, SC ;

Bredt, DS .

CELL, 1996, 84 (05) :757-767

[8] NITRIC-OXIDE SYNTHASE COMPLEXED WITH DYSTROPHIN AND ABSENT FROM SKELETAL-MUSCLE SARCOLEMMA IN DUCHENNE MUSCULAR-DYSTROPHY [J].

BRENMAN, JE ;

CHAO, DS ;

XIA, HH ;

ALDAPE, K ;

BREDT, DS .

CELL, 1995, 82 (05) :743-752

[9] Urinary bladder urethral sphincter dysfunction in mice with targeted disruption of neuronal nitric oxide synthase models idiopathic voiding disorders in humans [J].

Burnett, AL ;

Calvin, DC ;

Chamness, SL ;

Liu, JX ;

Nelson, RJ ;

Klein, SL ;

Dawson, VL ;

Dawson, TM ;

Snyder, SH .

NATURE MEDICINE, 1997, 3 (05) :571-574

[10] Nitric oxide-dependent penile erection in mice lacking neuronal nitric oxide synthase [J].

Burnett, AL ;

Nelson, RJ ;

Calvin, DC ;

Liu, JX ;

Demas, GE ;

Klein, SL ;

Kriegsfeld, LJ ;

Dawson, VL ;

Dawson, TM ;

Snyder, SH .

MOLECULAR MEDICINE, 1996, 2 (03) :288-296

← 1 2 3 4 5 6 7 8 9 10 →