Challenges in the Pharmacogenomic Annotation of Whole Genomes

被引：17

作者：

Altman, R. B. ^{[1
,2
]}

Whirl-Carrillo, M. ^{[1
]}

Klein, T. E. ^{[1
]}

机构：

[1] Stanford Univ, Dept Genet, Stanford, CA 94305 USA

[2] Stanford Univ, Dept Bioengn, Stanford, CA 94305 USA

来源：

CLINICAL PHARMACOLOGY & THERAPEUTICS | 2013年 / 94卷 / 02期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1038/clpt.2013.111

中图分类号：

R9 [药学];

学科分类号：

100702 [药剂学];

摘要：

Next-generation sequencing technologies have enabled the sequencing of an entire genome for less than $4,000. With access to all the genetic variation in an individual, our task will be to use this information to assess the genetic influences on drug efficacy, toxicity, and dosage.

引用

页码：211 / 213

页数：3

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