Studies toward the discovery of the next generation of antidepressants.: Part 2:: Incorporating a 5-HT1A antagonist component into a class of serotonin reuptake inhibitors

被引：37

作者：

Mewshaw, RE

Meagher, KL

Zhou, P

Zhou, DH

Shi, XJ

Scerni, R

Smith, D

Schechter, LE

Andree, TH

机构：

[1] Wyeth Ayerst Res Labs, Global Chem Sci Dept, Philadelphia, PA 19101 USA

[2] Wyeth Ayerst Res Labs, Dept Neurosci, Philadelphia, PA 19101 USA

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 2002年 / 12卷 / 03期

关键词：

D O I：

10.1016/S0960-894X(01)00746-6

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The design and synthesis of a novel series of indole derivatives (9) having dual 5-HT transporter reuptake and 5-HT1A antagonist activity are described. (C) 2002 Elsevier Science Ltd. All rights reserved.

引用

页码：307 / 310

页数：4

共 31 条

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