Chemokine receptors in lymphoid organ homeostasis

被引：48

作者：

Jung, S ^{[1
]}

Littman, DR ^{[1
]}

机构：

[1] NYU, Med Ctr, Howard Hughes Med Inst, Mol Pathogenesis Program,Skirball Inst Biomol Med, New York, NY 10016 USA

来源：

CURRENT OPINION IN IMMUNOLOGY | 1999年 / 11卷 / 03期

关键词：

D O I：

10.1016/S0952-7915(99)80051-X

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Leukocytes respond to complex patterns of chemoattractant cytokine (chemokine) gradients that guide them to their destinations in secondary lymphoid organs. This directed movement of multiple cell types requires the choreographed expression of specific G-protein-coupled chemokine receptors and both positive and negative regulation of the signal transduction pathways emanating from them.

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收藏

页码：319 / 325

页数：7

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