Validation of the COPD severity score for use in primary care: the NEREA study

被引：39

作者：

Miravitlles, M. ^{[1
]}

Llor, C. ^{[2
]}

de Castellar, R. ^{[3
]}

Izquierdo, I. ^{[5
]}

Baro, E. ^{[4
]}

Donado, E. ^{[5
]}

机构：

[1] Hosp Clin Barcelona, Serv Pneumol, Dept Pneumol, Clin Inst Thorax, Barcelona 08036, Spain

[2] Univ Rovira & Virgili, Primary Hlth Care Ctr Jaume I, Catalan Soc Family Med, Tarragona, Spain

[3] R&D&I Unit, Barcelona, Spain

[4] Project Management Dept 3D Hlth Res, Barcelona, Spain

[5] J Uriach & Co, Clin Dev & Med Advice, Palau Solita Plegamans, Spain

来源：

EUROPEAN RESPIRATORY JOURNAL | 2009年 / 33卷 / 03期

关键词：

Chronic obstructive pulmonary disease; outcome assessment; primary care; questionnaires; OBSTRUCTIVE PULMONARY-DISEASE; QUALITY-OF-LIFE; LONDON CHEST ACTIVITY; PHYSICAL-ACTIVITY; GENERAL-PRACTICE; SPANISH VERSION; EXACERBATIONS; POPULATION; SPIROMETRY; DYSPNEA;

D O I：

10.1183/09031936.00087208

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

Spirometry is underused for the assessment of severity of chronic obstructive pulmonary disease (COPD) in primary care (PC). Therefore, simple assessment tools are required in this setting. The aim of the present study was to validate the COPD severity score (COPDSS) for use in PC. A multicentric study was carried out in stable COPD patients in PC. The concurrent validity of the COPDSS was evaluated by examining the association between COPDSS, COPD clinical indicators and the London Chest Activity of Daily Living (LCADL) scale, European quality of life (EuroQOL) questionnaires and Charlson comorbidity index. A total of 837 patients with COPD were analysed (males 84.3%; mean +/- SD age 68 +/- 11 yrs; forced expiratory volume in one second 54.6 +/- 17.7% of the predicted value). A strong correlation was found between COPDSS and dyspnoea level and a moderate correlation between COPDSS and exacerbation number. The COPDSS discriminated between patients with varying degrees of dyspnoea (area under receiver operating characteristic (ROC) curve 0.837), and according to number of exacerbations in the last year (area under ROC curve 0.773). Higher COPDSS scores were significantly associated with lower EuroQOL scores, lower EuroQOL visual analogue scale scores and higher LCADL scores. The present results indicate that the chronic obstructive pulmonary disease severity score is a useful and reliable tool for assessing the severity of chronic obstructive pulmonary disease in primary care.

引用

页码：519 / 527

页数：9