Contribution of sialic acid-binding adhesin to pathogenesis of experimental endocarditis caused by Streptococcus gordonii DL1

被引：71

作者：

Takahashi, Y

Takashima, E

Shimazu, K

Yagishita, H

Aoba, T

Konishi, K

机构：

[1] Nippon Dent Univ Sch Dent Tokyo, Dept Microbiol, Chiyoda Ku, Tokyo 1028159, Japan

[2] Nippon Dent Univ Sch Dent Tokyo, Dept Pediat Dent, Chiyoda Ku, Tokyo 1028159, Japan

[3] Nippon Dent Univ Sch Dent Tokyo, Dept Pathol, Chiyoda Ku, Tokyo 1028159, Japan

来源：

INFECTION AND IMMUNITY | 2006年 / 74卷 / 01期

关键词：

D O I：

10.1128/IAI.74.1.740-743.2006

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

An insertional mutation in hsa, the gene encoding the sialic acid-binding adhesin of Streptococcus gordonii DL1, resulted in a significant reduction of the infection rate of the organism and an inflammatory reaction in the rat aortic valve with experimental endocarditis, suggesting that the adhesin contributes to the infectivity of the organism for heart valves.

引用

页码：740 / 743

页数：4

共 25 条

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