Palladium-tetraphosphine complex:: An efficient catalyst for the alkynylation of ortho-substituted aryl bromides

被引：39

作者：

Feuerstein, M ^{[1
]}

Berthiol, F ^{[1
]}

Doucet, H ^{[1
]}

Santelli, M ^{[1
]}

机构：

[1] Univ Aix Marseille 3, Organ Synth Lab, CNRS, UMR 6180,Fac Sci St Jerome, F-13397 Marseille 20, France

来源：

SYNTHESIS-STUTTGART | 2004年 / 08期

关键词：

palladium; tetraphosphine; catalysis; alkynylation; alkynes; aryl bromides;

D O I：

10.1055/s-2004-822354

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The tetraphosphine cis,cis,cis-1,2,3,4-tetrakis(diphenylphosphinomethyl)cyclopentane in combination with [Pd(C3H5)Cl](2) affords a very efficient catalyst for the alkynylation of ortho-substituted aryl bromides. A wide variety of substituents such as phenyl, trifluoromethyl, acetyl, formyl or nitrile, are tolerated. High turnover numbers can be obtained with most of these aryl bromides. The coupling of sterically very congested aryl bromides such as 9-bromoanthracene or 2,4,6-triisopropylbromobenzene also proceeds in good yields.

引用

页码：1281 / 1289

页数：9

共 48 条

[31] SINGLET OXYGEN OXIDATION OF SUBSTITUTED FURANS TO 5-HYDROXY-2(5H)-FURANONE [J].