Th17 Cells Regulate Liver Fibrosis by Targeting Multiple Cell Types: Many Birds With One Stone

被引:37
作者
Gao, Bin [1 ]
Waisman, Ari [2 ]
机构
[1] NIAAA, Lab Liver Dis, NIH, Bethesda, MD 20892 USA
[2] Johannes Gutenberg Univ Mainz, Univ Med Ctr, Inst Mol Med, Mainz, Germany
关键词
IL-17; INTERLEUKIN-22; HEPATOCYTES; CYTOKINES; HEPATITIS; IL-22;
D O I
10.1053/j.gastro.2012.07.031
中图分类号
R57 [消化系及腹部疾病];
学科分类号
100201 [内科学];
摘要
引用
收藏
页码:536 / 539
页数:4
相关论文
共 20 条
[1]
Selective depletion of macrophages reveals distinct, opposing roles during liver injury and repair [J].
Duffield, JS ;
Forbes, SJ ;
Constandinou, CM ;
Clay, S ;
Partolina, M ;
Vuthoori, S ;
Wu, SJ ;
Lang, R ;
Iredale, JP .
JOURNAL OF CLINICAL INVESTIGATION, 2005, 115 (01) :56-65
[2]
Interleukin-22 Promotes Proliferation of Liver Stem/Progenitor Cells in Mice and Patients With Chronic Hepatitis B Virus Infection [J].
Feng, Dechun ;
Kong, Xiaoni ;
Weng, Honglei ;
Park, Ogyi ;
Wang, Hua ;
Dooley, Steven ;
Gershwin, M. Eric ;
Gao, Bin .
GASTROENTEROLOGY, 2012, 143 (01) :188-U375
[3]
Recent advances in the IL-17 cytokine family [J].
Gaffen, Sarah L. .
CURRENT OPINION IN IMMUNOLOGY, 2011, 23 (05) :613-619
[4]
Interleukin-22 induces hepatic stellate cell senescence and restricts liver fibrosis in mice [J].
Kong, Xiaoni ;
Feng, Dechun ;
Wang, Hua ;
Hong, Feng ;
Bertola, Adeline ;
Wang, Fu-Sheng ;
Gao, Bin .
HEPATOLOGY, 2012, 56 (03) :1150-1159
[5]
IL-17 and Th17 Cells [J].
Korn, Thomas ;
Bettelli, Estelle ;
Oukka, Mohamed ;
Kuchroo, Vijay K. .
ANNUAL REVIEW OF IMMUNOLOGY, 2009, 27 :485-517
[6]
Th17 cells and their associated cytokines in liver diseases [J].
Lafdil, Fouad ;
Miller, Andrew M. ;
Ki, Sung Hwan ;
Gao, Bin .
CELLULAR & MOLECULAR IMMUNOLOGY, 2010, 7 (04) :250-254
[7]
Myeloid STAT3 Inhibits T Cell-Mediated Hepatitis by Regulating T Helper 1 Cytokine and Interleukin-17 Production [J].
Lafdil, Fouad ;
Wang, Hua ;
Park, Ogyi ;
Zhang, Weici ;
Moritoki, Yuki ;
Yin, Shi ;
Fu, Xin Yuan ;
Gershwin, M. Eric ;
Lian, Zhe-Xiong ;
Gao, Bin .
GASTROENTEROLOGY, 2009, 137 (06) :2125-2135
[8]
The Interleukin-17 Pathway Is Involved in Human Alcoholic Liver Disease [J].
Lemmers, Arnaud ;
Moreno, Christophe ;
Gustot, Thierry ;
Marechal, Raphael ;
Degre, Delphine ;
Demetter, Pieter ;
de Nadai, Patricia ;
Geerts, Albert ;
Quertinmont, Eric ;
Vercruysse, Vincent ;
Le Moine, Olivier ;
Deviere, Jacques .
HEPATOLOGY, 2009, 49 (02) :646-657
[9]
Inhibition of Interleukin-17 Promotes Differentiation of CD25- Cells Into Stable T Regulatory Cells in Patients With Autoimmune Hepatitis [J].
Longhi, Maria Serena ;
Liberal, Rodrigo ;
Holder, Beth ;
Robson, Simon C. ;
Ma, Yun ;
Mieli-Vergani, Giorgina ;
Vergani, Diego .
GASTROENTEROLOGY, 2012, 142 (07) :1526-+
[10]
Interleukin-17 Signaling in Inflammatory, Kupffer Cells, and Hepatic Stellate Cells Exacerbates Liver Fibrosis in Mice [J].
Meng, Fanli ;
Wang, Kai ;
Aoyama, Tomonori ;
Grivennikov, Sergei I. ;
Paik, Yonghan ;
Scholten, David ;
Cong, Min ;
Iwaisako, Keiko ;
Liu, Xiao ;
Zhang, Mingjun ;
Oesterreicher, Christoph H. ;
Stickel, Felix ;
Ley, Klaus ;
Brenner, David A. ;
Kisseleva, Tatiana .
GASTROENTEROLOGY, 2012, 143 (03) :765-+