Toxic epidermal necrolysis-like reaction secondary to colchicine overdose

被引：20

作者：

Arroyo, MP

Sanders, S

Yee, H

Schwartz, D

Kamino, H

Strober, BE

机构：

[1] NYU, Sch Med, Ronald O Perelman Dept Dermatol, New York, NY 10016 USA

[2] NYU, Sch Med, Dept Pathol, New York, NY 10016 USA

[3] NYU, Sch Med, Dept Med, New York, NY 10016 USA

来源：

BRITISH JOURNAL OF DERMATOLOGY | 2004年 / 150卷 / 03期

关键词：

apoptosis; colchicine; overdose; skin; toxic epidermal necrolysis;

D O I：

10.1111/j.1365-2133.2004.05838.x

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 [皮肤病与性病学];

摘要：

Colchicine is a microtubule-inhibiting drug used to treat gout, familial Mediterranean fever and many other skin diseases. Intoxication with colchicine affects multiple organs, often fatally. Cutaneous sequelae of colchicine toxicity are rare. We describe the clinical and histological features of a toxic epidermal necrolysis-like exanthem in a patient who lethally overdosed on colchicine.

引用

页码：581 / 588

页数：8

共 75 条

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TOXIC EPIDERMAL NECROLYSIS IN A PATIENT SUFFERING FROM ACQUIRED-IMMUNE-DEFICIENCY-SYNDROME [J].