Calcium-myristoyl switches turn on new lights

被引:17
作者
Meyer, T [1 ]
York, JD
机构
[1] Duke Univ, Med Ctr, Dept Cell Biol, Durham, NC 27710 USA
[2] Duke Univ, Med Ctr, Dept Pharmacol, Durham, NC 27710 USA
[3] Duke Univ, Med Ctr, Dept Canc Biol, Durham, NC 27710 USA
[4] Duke Univ, Med Ctr, Dept Biochem, Durham, NC 27710 USA
关键词
D O I
10.1038/12090
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
The yeast homologue of the calcium-myristoyl-switch protein frequenin activates a key enzyme in the phosphoinositide signalling cascade, shedding new light on the role of such switch proteins ana of calcium signalling.
引用
收藏
页码:E93 / E95
页数:3
相关论文
共 15 条
[1]   Molecular mechanics of calcium-myristoyl switches [J].
Ames, JB ;
Ishima, R ;
Tanaka, T ;
Gordon, JI ;
Stryer, L ;
Ikura, M .
NATURE, 1997, 389 (6647) :198-202
[2]   Phosphoinositides as regulators in membrane traffic [J].
DeCamilli, P ;
Emr, SD ;
McPherson, PS ;
Novick, P .
SCIENCE, 1996, 271 (5255) :1533-1539
[3]   MSS4, a phosphatidylinositol-4-phosphate 5-kinase required for organization of the actin cytoskeleton in Saccharomyces cerevisiae [J].
Desrivières, S ;
Cooke, FT ;
Parker, PJ ;
Hall, MN .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (25) :15787-15793
[4]   ROLE OF THE ACYLATED AMINO TERMINUS OF RECOVERIN IN CA2+-DEPENDENT MEMBRANE INTERACTION [J].
DIZHOOR, AM ;
CHEN, CK ;
OLSHEVSKAYA, E ;
SINELNIKOVA, VV ;
PHILLIPOV, P ;
HURLEY, JB .
SCIENCE, 1993, 259 (5096) :829-832
[5]   3-DIMENSIONAL STRUCTURE OF RECOVERIN, A CALCIUM SENSOR IN VISION [J].
FLAHERTY, KM ;
ZOZULYA, S ;
STRYER, L ;
MCKAY, DB .
CELL, 1993, 75 (04) :709-716
[6]  
FURMAN DA, 1998, ANNU REV BIOCHEM, V67, P481
[7]   SAC1-like domains of yeast SAC1, INP52, and INP53 and of human synaptojanin encode polyphosphoinositide phosphatases [J].
Guo, SL ;
Stolz, LE ;
Lemrow, SM ;
York, JD .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1999, 274 (19) :12990-12995
[8]   Yeast homologue of neuronal frequenin is a regulator of phosphatidylinositol-4-OH kinase [J].
Hendricks, KB ;
Wang, BQ ;
Schnieders, EA ;
Thorner, J .
NATURE CELL BIOLOGY, 1999, 1 (04) :234-241
[9]   SIGNIFICANCE OF PIP2 HYDROLYSIS AND REGULATION OF PHOSPHOLIPASE-C ISOZYMES [J].
LEE, SB ;
RHEE, SG .
CURRENT OPINION IN CELL BIOLOGY, 1995, 7 (02) :183-189
[10]   Calcium binding, but not a calcium-myristoyl switch, controls the ability of guanylyl cyclase-activating protein GCAP-2 to regulate photoreceptor guanylyl cyclase [J].
Olshevskaya, EV ;
Hughes, RE ;
Hurley, JB ;
Dizhoor, AM .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1997, 272 (22) :14327-14333