A variety of mechanisms are used to signal extracytoplasmic conditions to the cytoplasm. These mechanisms activate extracytoplasmic function (ECF) sigma factors which recruit RNA-polymerase to specific genes in order to express appropriate proteins in response to the changing environment. The two best understood ECF signaling pathways regulate sigma(E)-mediated expression of periplasmic stress response genes in Escherichia coli and Fecl-mediated expression of iron-citrate transport genes in E. coli. Homologues from other Gram-negative bacteria suggest that these two signaling mechanisms and variations on these mechanisms may be the general schemes by which ECF sigma factors are regulated in Gram-negative bacteria. Published by Elsevier B.V.
机构:Univ Calif San Francisco, Dept Microbiol & Immunol, San Francisco, CA 94143 USA
Alba, BM
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Leeds, JA
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机构:Univ Calif San Francisco, Dept Microbiol & Immunol, San Francisco, CA 94143 USA
Leeds, JA
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Onufryk, C
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机构:Univ Calif San Francisco, Dept Microbiol & Immunol, San Francisco, CA 94143 USA
Onufryk, C
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Lu, CZ
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机构:Univ Calif San Francisco, Dept Microbiol & Immunol, San Francisco, CA 94143 USA
Lu, CZ
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Gross, CA
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Univ Calif San Francisco, Dept Microbiol & Immunol, San Francisco, CA 94143 USAUniv Calif San Francisco, Dept Microbiol & Immunol, San Francisco, CA 94143 USA
机构:Univ Calif San Francisco, Dept Microbiol & Immunol, San Francisco, CA 94143 USA
Alba, BM
;
Leeds, JA
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机构:Univ Calif San Francisco, Dept Microbiol & Immunol, San Francisco, CA 94143 USA
Leeds, JA
;
Onufryk, C
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机构:Univ Calif San Francisco, Dept Microbiol & Immunol, San Francisco, CA 94143 USA
Onufryk, C
;
Lu, CZ
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h-index: 0
机构:Univ Calif San Francisco, Dept Microbiol & Immunol, San Francisco, CA 94143 USA
Lu, CZ
;
Gross, CA
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Univ Calif San Francisco, Dept Microbiol & Immunol, San Francisco, CA 94143 USAUniv Calif San Francisco, Dept Microbiol & Immunol, San Francisco, CA 94143 USA