IL-1 and IL-18 receptors, and their extended family

被引：168

作者：

Sims, JE ^{[1
]}

机构：

[1] Immunex Res & Dev Corp, Seattle, WA 98101 USA

来源：

CURRENT OPINION IN IMMUNOLOGY | 2002年 / 14卷 / 01期

关键词：

D O I：

10.1016/S0952-7915(01)00306-5

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The cytokines IL-1 and IL-18 are key molecules in both the innate and the adaptive immune response. Recently, important insights have been gained into the regulation of their functions. Moreover, it has become apparent that they are members of a larger family of related receptors, some of which can also be shown to contribute to host defense.

引用

页码：117 / 122

页数：6

共 61 条

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