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Oral delivery of peptides: opportunities and issues for translation
被引:50
作者
:
Brayden, David J.
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Coll Dublin, UCD Sch Vet Med, Dublin 4, Ireland
Univ Coll Dublin, Conway Inst, Dublin 4, Ireland
Univ Coll Dublin, UCD Sch Vet Med, Dublin 4, Ireland
Brayden, David J.
[
1
,
2
]
Alonso, Maria-Jose
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Santiago Compostela, CIMUS Res Inst, Dept Pharm & Pharmaceut Technol, Campus Vida, Santiago De Compostela 15706, Spain
Univ Coll Dublin, UCD Sch Vet Med, Dublin 4, Ireland
Alonso, Maria-Jose
[
3
]
机构
:
[1]
Univ Coll Dublin, UCD Sch Vet Med, Dublin 4, Ireland
[2]
Univ Coll Dublin, Conway Inst, Dublin 4, Ireland
[3]
Univ Santiago Compostela, CIMUS Res Inst, Dept Pharm & Pharmaceut Technol, Campus Vida, Santiago De Compostela 15706, Spain
来源
:
ADVANCED DRUG DELIVERY REVIEWS
|
2016年
/ 106卷
关键词
:
oral peptide delivery;
nanomedicines;
nanocarriers;
intestinal permeation enhancers;
nanotoxicology;
anti-diabetic peptides;
D O I
:
10.1016/j.addr.2016.10.005
中图分类号
:
R9 [药学];
学科分类号
:
100702
[药剂学]
;
摘要
:
引用
收藏
页码:193 / 195
页数:3
相关论文
共 19 条
[1]
Current status of selected oral peptide technologies in advanced preclinical development and in clinical trials
[J].
Aguirre, T. A. S.
论文数:
0
引用数:
0
h-index:
0
机构:
UCS, Ctr Ciencias Exatas & Tecnol, Caxias Do Sul, Brazil
UCS, Ctr Ciencias Exatas & Tecnol, Caxias Do Sul, Brazil
Aguirre, T. A. S.
;
Teijeiro-Osorio, D.
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Santiago Compostela, CIMUS Res Inst, Santiago De Compostela, Spain
UCS, Ctr Ciencias Exatas & Tecnol, Caxias Do Sul, Brazil
Teijeiro-Osorio, D.
;
Rosa, M.
论文数:
0
引用数:
0
h-index:
0
机构:
Dublin City Univ, Invent Ctr, Sigmoid Pharma, Dublin 9, Ireland
UCS, Ctr Ciencias Exatas & Tecnol, Caxias Do Sul, Brazil
Rosa, M.
;
Coulter, I. S.
论文数:
0
引用数:
0
h-index:
0
机构:
Dublin City Univ, Invent Ctr, Sigmoid Pharma, Dublin 9, Ireland
UCS, Ctr Ciencias Exatas & Tecnol, Caxias Do Sul, Brazil
Coulter, I. S.
;
Alonso, M. J.
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Santiago Compostela, CIMUS Res Inst, Santiago De Compostela, Spain
UCS, Ctr Ciencias Exatas & Tecnol, Caxias Do Sul, Brazil
Alonso, M. J.
;
Brayden, D. J.
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Coll Dublin, UCD Sch Vet Med, Dublin 4, Ireland
Univ Coll Dublin, UCD Conway Inst, Dublin 4, Ireland
UCS, Ctr Ciencias Exatas & Tecnol, Caxias Do Sul, Brazil
Brayden, D. J.
.
ADVANCED DRUG DELIVERY REVIEWS,
2016,
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-241
[2]
Mechanisms of transport of polymeric and lipidic nanoparticles across the intestinal barrier
[J].
Beloqui, Ana
论文数:
0
引用数:
0
h-index:
0
机构:
Catholic Univ Louvain, Louvain Drug Res Inst, Adv Drug Delivery & Biomat, Ave Mounier 73 Bte B1 73-12, B-1200 Brussels, Belgium
Catholic Univ Louvain, Louvain Drug Res Inst, Adv Drug Delivery & Biomat, Ave Mounier 73 Bte B1 73-12, B-1200 Brussels, Belgium
Beloqui, Ana
;
des Rieux, Anne
论文数:
0
引用数:
0
h-index:
0
机构:
Catholic Univ Louvain, Louvain Drug Res Inst, Adv Drug Delivery & Biomat, Ave Mounier 73 Bte B1 73-12, B-1200 Brussels, Belgium
Catholic Univ Louvain, Inst Condensed Matter & Nanosci, B-1348 Louvain La Neuve, Belgium
Catholic Univ Louvain, Louvain Drug Res Inst, Adv Drug Delivery & Biomat, Ave Mounier 73 Bte B1 73-12, B-1200 Brussels, Belgium
des Rieux, Anne
;
Preat, Veronique
论文数:
0
引用数:
0
h-index:
0
机构:
Catholic Univ Louvain, Louvain Drug Res Inst, Adv Drug Delivery & Biomat, Ave Mounier 73 Bte B1 73-12, B-1200 Brussels, Belgium
Catholic Univ Louvain, Louvain Drug Res Inst, Adv Drug Delivery & Biomat, Ave Mounier 73 Bte B1 73-12, B-1200 Brussels, Belgium
Preat, Veronique
.
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2016,
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-255
[3]
Chemically modified peptides and proteins - critical considerations for oral delivery
[J].
Buckley, Stephen T.
论文数:
0
引用数:
0
h-index:
0
机构:
Novo Nordisk AS, Global Res, Novo Nordisk Pk, DK-2760 Malov, Denmark
Novo Nordisk AS, Global Res, Novo Nordisk Pk, DK-2760 Malov, Denmark
Buckley, Stephen T.
;
Hubalek, Frantisek
论文数:
0
引用数:
0
h-index:
0
机构:
Novo Nordisk AS, Global Res, Novo Nordisk Pk, DK-2760 Malov, Denmark
Novo Nordisk AS, Global Res, Novo Nordisk Pk, DK-2760 Malov, Denmark
Hubalek, Frantisek
;
Rahbek, Ulrik Lytt
论文数:
0
引用数:
0
h-index:
0
机构:
Novo Nordisk AS, Global Res, Novo Nordisk Pk, DK-2760 Malov, Denmark
Novo Nordisk AS, Global Res, Novo Nordisk Pk, DK-2760 Malov, Denmark
Rahbek, Ulrik Lytt
.
TISSUE BARRIERS,
2016,
4
(02)
[4]
In vitro toxicity assessment of oral nanocarriers
[J].
Ciappellano, Silvia Gabriella
论文数:
0
引用数:
0
h-index:
0
机构:
ECAMRICERT SRL, ECSIN, Viale Porta Adige 45, I-45100 Rovigo, Italy
ECAMRICERT SRL, ECSIN, Viale Porta Adige 45, I-45100 Rovigo, Italy
Ciappellano, Silvia Gabriella
;
Tedesco, Erik
论文数:
0
引用数:
0
h-index:
0
机构:
ECAMRICERT SRL, ECSIN, Viale Porta Adige 45, I-45100 Rovigo, Italy
ECAMRICERT SRL, ECSIN, Viale Porta Adige 45, I-45100 Rovigo, Italy
Tedesco, Erik
;
Venturini, Marco
论文数:
0
引用数:
0
h-index:
0
机构:
ECAMRICERT SRL, ECSIN, Viale Porta Adige 45, I-45100 Rovigo, Italy
ECAMRICERT SRL, ECSIN, Viale Porta Adige 45, I-45100 Rovigo, Italy
Venturini, Marco
;
Benetti, Federico
论文数:
0
引用数:
0
h-index:
0
机构:
ECAMRICERT SRL, ECSIN, Viale Porta Adige 45, I-45100 Rovigo, Italy
ECAMRICERT SRL, ECSIN, Viale Porta Adige 45, I-45100 Rovigo, Italy
Benetti, Federico
.
ADVANCED DRUG DELIVERY REVIEWS,
2016,
106
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-401
[5]
NEW APPROACH FOR ORAL-ADMINISTRATION OF INSULIN WITH POLYALKYLCYANOACRYLATE NANOCAPSULES AS DRUG CARRIER
[J].
DAMGE, C
论文数:
0
引用数:
0
h-index:
0
机构:
UNIV PARIS 11, PHARM GALEN & BIOPHARM LAB, F-92290 CHATENAY MALABRY, FRANCE
UNIV PARIS 11, PHARM GALEN & BIOPHARM LAB, F-92290 CHATENAY MALABRY, FRANCE
DAMGE, C
;
论文数:
引用数:
h-index:
机构:
MICHEL, C
;
APRAHAMIAN, M
论文数:
0
引用数:
0
h-index:
0
机构:
UNIV PARIS 11, PHARM GALEN & BIOPHARM LAB, F-92290 CHATENAY MALABRY, FRANCE
UNIV PARIS 11, PHARM GALEN & BIOPHARM LAB, F-92290 CHATENAY MALABRY, FRANCE
APRAHAMIAN, M
;
论文数:
引用数:
h-index:
机构:
COUVREUR, P
.
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Design and Development of a Cyclic Decapeptide Scaffold with Suitable Properties for Bioavailability and Oral Exposure
[J].
Fouche, Marianne
论文数:
0
引用数:
0
h-index:
0
机构:
Novartis Inst BioMed Res, Global Discovery Chem Macrocycles, CH-4002 Basel, Switzerland
Novartis Inst BioMed Res, Global Discovery Chem Macrocycles, CH-4002 Basel, Switzerland
Fouche, Marianne
;
Schafer, Michael
论文数:
0
引用数:
0
h-index:
0
机构:
Novartis Inst BioMed Res, Global Discovery Chem CADD, CH-4002 Basel, Switzerland
Novartis Inst BioMed Res, Global Discovery Chem Macrocycles, CH-4002 Basel, Switzerland
Schafer, Michael
;
Berghausen, Jorg
论文数:
0
引用数:
0
h-index:
0
机构:
Novartis Inst BioMed Res, Metab & Pharmacokinet, CH-4002 Basel, Switzerland
Novartis Inst BioMed Res, Global Discovery Chem Macrocycles, CH-4002 Basel, Switzerland
Berghausen, Jorg
;
Desrayaud, Sandrine
论文数:
0
引用数:
0
h-index:
0
机构:
Novartis Inst BioMed Res, Metab & Pharmacokinet, CH-4002 Basel, Switzerland
Novartis Inst BioMed Res, Global Discovery Chem Macrocycles, CH-4002 Basel, Switzerland
Desrayaud, Sandrine
;
Blatter, Markus
论文数:
0
引用数:
0
h-index:
0
机构:
Novartis Inst BioMed Res, Global Discovery Chem Analyt NMR, CH-4002 Basel, Switzerland
Novartis Inst BioMed Res, Global Discovery Chem Macrocycles, CH-4002 Basel, Switzerland
Blatter, Markus
;
Piechon, Philippe
论文数:
0
引用数:
0
h-index:
0
机构:
Novartis Inst BioMed Res, Global Discovery Chem Analyt Crystallog, CH-4002 Basel, Switzerland
Novartis Inst BioMed Res, Global Discovery Chem Macrocycles, CH-4002 Basel, Switzerland
Piechon, Philippe
;
Dix, Ina
论文数:
0
引用数:
0
h-index:
0
机构:
Novartis Inst BioMed Res, Global Discovery Chem Analyt Crystallog, CH-4002 Basel, Switzerland
Novartis Inst BioMed Res, Global Discovery Chem Macrocycles, CH-4002 Basel, Switzerland
Dix, Ina
;
论文数:
引用数:
h-index:
机构:
Martin Garcia, Aimar
;
Roth, Hans-Jorg
论文数:
0
引用数:
0
h-index:
0
机构:
Novartis Inst BioMed Res, Global Discovery Chem Macrocycles, CH-4002 Basel, Switzerland
Novartis Inst BioMed Res, Global Discovery Chem Macrocycles, CH-4002 Basel, Switzerland
Roth, Hans-Jorg
.
CHEMMEDCHEM,
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Pharmacokinetic, pharmacodynamic and biodistribution following oral administration of nanocarriers containing peptide and protein drugs
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Griffin, Brendan T.
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0
引用数:
0
h-index:
0
机构:
Univ Coll Cork, Sch Pharm, Cavanagh Pharm Bldg, Cork, Ireland
Univ Coll Cork, Sch Pharm, Cavanagh Pharm Bldg, Cork, Ireland
Griffin, Brendan T.
;
Guo, Jianfeng
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Coll Cork, Sch Pharm, Cavanagh Pharm Bldg, Cork, Ireland
Univ Coll Cork, Sch Pharm, Cavanagh Pharm Bldg, Cork, Ireland
Guo, Jianfeng
;
Presas, Elena
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Coll Cork, Sch Pharm, Cavanagh Pharm Bldg, Cork, Ireland
Univ Coll Cork, Sch Pharm, Cavanagh Pharm Bldg, Cork, Ireland
Presas, Elena
;
Donovan, Maria D.
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Coll Cork, Sch Pharm, Cavanagh Pharm Bldg, Cork, Ireland
Univ Coll Cork, Sch Pharm, Cavanagh Pharm Bldg, Cork, Ireland
Donovan, Maria D.
;
Alonso, Maria J.
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Santiago Compostela, CIMUS Res Inst, Santiago De Compostela, Spain
Univ Coll Cork, Sch Pharm, Cavanagh Pharm Bldg, Cork, Ireland
Alonso, Maria J.
;
O'Driscoll, Caitriona M.
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Coll Cork, Sch Pharm, Cavanagh Pharm Bldg, Cork, Ireland
Univ Coll Cork, Sch Pharm, Cavanagh Pharm Bldg, Cork, Ireland
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引用数:
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Lundquist, P.
;
Artursson, P.
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0
引用数:
0
h-index:
0
机构:
Uppsala Univ, Dept Pharm, Box 580, SE-75237 Uppsala, Sweden
Uppsala Univ, Dept Pharm, Box 580, SE-75237 Uppsala, Sweden
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2016,
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Intestinal permeation enhancers for oral peptide delivery
[J].
Maher, Sam
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0
引用数:
0
h-index:
0
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Royal Coll Surgeons Ireland, RCSI Sch Pharm, Dublin 2, Ireland
Royal Coll Surgeons Ireland, RCSI Sch Pharm, Dublin 2, Ireland
Maher, Sam
;
Mrsny, Randall J.
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Bath, Dept Pharm & Pharmacol, Bath BA2 7AY, Avon, England
Royal Coll Surgeons Ireland, RCSI Sch Pharm, Dublin 2, Ireland
Mrsny, Randall J.
;
Brayden, David J.
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Coll Dublin, UCD Sch Vet Med, Dublin 4, Ireland
Univ Coll Dublin, Conway Inst, Dublin 4, Ireland
Royal Coll Surgeons Ireland, RCSI Sch Pharm, Dublin 2, Ireland
Brayden, David J.
.
ADVANCED DRUG DELIVERY REVIEWS,
2016,
106
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-319
←
1
2
→
共 19 条
[1]
Current status of selected oral peptide technologies in advanced preclinical development and in clinical trials
[J].
Aguirre, T. A. S.
论文数:
0
引用数:
0
h-index:
0
机构:
UCS, Ctr Ciencias Exatas & Tecnol, Caxias Do Sul, Brazil
UCS, Ctr Ciencias Exatas & Tecnol, Caxias Do Sul, Brazil
Aguirre, T. A. S.
;
Teijeiro-Osorio, D.
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Santiago Compostela, CIMUS Res Inst, Santiago De Compostela, Spain
UCS, Ctr Ciencias Exatas & Tecnol, Caxias Do Sul, Brazil
Teijeiro-Osorio, D.
;
Rosa, M.
论文数:
0
引用数:
0
h-index:
0
机构:
Dublin City Univ, Invent Ctr, Sigmoid Pharma, Dublin 9, Ireland
UCS, Ctr Ciencias Exatas & Tecnol, Caxias Do Sul, Brazil
Rosa, M.
;
Coulter, I. S.
论文数:
0
引用数:
0
h-index:
0
机构:
Dublin City Univ, Invent Ctr, Sigmoid Pharma, Dublin 9, Ireland
UCS, Ctr Ciencias Exatas & Tecnol, Caxias Do Sul, Brazil
Coulter, I. S.
;
Alonso, M. J.
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Santiago Compostela, CIMUS Res Inst, Santiago De Compostela, Spain
UCS, Ctr Ciencias Exatas & Tecnol, Caxias Do Sul, Brazil
Alonso, M. J.
;
Brayden, D. J.
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Coll Dublin, UCD Sch Vet Med, Dublin 4, Ireland
Univ Coll Dublin, UCD Conway Inst, Dublin 4, Ireland
UCS, Ctr Ciencias Exatas & Tecnol, Caxias Do Sul, Brazil
Brayden, D. J.
.
ADVANCED DRUG DELIVERY REVIEWS,
2016,
106
:223
-241
[2]
Mechanisms of transport of polymeric and lipidic nanoparticles across the intestinal barrier
[J].
Beloqui, Ana
论文数:
0
引用数:
0
h-index:
0
机构:
Catholic Univ Louvain, Louvain Drug Res Inst, Adv Drug Delivery & Biomat, Ave Mounier 73 Bte B1 73-12, B-1200 Brussels, Belgium
Catholic Univ Louvain, Louvain Drug Res Inst, Adv Drug Delivery & Biomat, Ave Mounier 73 Bte B1 73-12, B-1200 Brussels, Belgium
Beloqui, Ana
;
des Rieux, Anne
论文数:
0
引用数:
0
h-index:
0
机构:
Catholic Univ Louvain, Louvain Drug Res Inst, Adv Drug Delivery & Biomat, Ave Mounier 73 Bte B1 73-12, B-1200 Brussels, Belgium
Catholic Univ Louvain, Inst Condensed Matter & Nanosci, B-1348 Louvain La Neuve, Belgium
Catholic Univ Louvain, Louvain Drug Res Inst, Adv Drug Delivery & Biomat, Ave Mounier 73 Bte B1 73-12, B-1200 Brussels, Belgium
des Rieux, Anne
;
Preat, Veronique
论文数:
0
引用数:
0
h-index:
0
机构:
Catholic Univ Louvain, Louvain Drug Res Inst, Adv Drug Delivery & Biomat, Ave Mounier 73 Bte B1 73-12, B-1200 Brussels, Belgium
Catholic Univ Louvain, Louvain Drug Res Inst, Adv Drug Delivery & Biomat, Ave Mounier 73 Bte B1 73-12, B-1200 Brussels, Belgium
Preat, Veronique
.
ADVANCED DRUG DELIVERY REVIEWS,
2016,
106
:242
-255
[3]
Chemically modified peptides and proteins - critical considerations for oral delivery
[J].
Buckley, Stephen T.
论文数:
0
引用数:
0
h-index:
0
机构:
Novo Nordisk AS, Global Res, Novo Nordisk Pk, DK-2760 Malov, Denmark
Novo Nordisk AS, Global Res, Novo Nordisk Pk, DK-2760 Malov, Denmark
Buckley, Stephen T.
;
Hubalek, Frantisek
论文数:
0
引用数:
0
h-index:
0
机构:
Novo Nordisk AS, Global Res, Novo Nordisk Pk, DK-2760 Malov, Denmark
Novo Nordisk AS, Global Res, Novo Nordisk Pk, DK-2760 Malov, Denmark
Hubalek, Frantisek
;
Rahbek, Ulrik Lytt
论文数:
0
引用数:
0
h-index:
0
机构:
Novo Nordisk AS, Global Res, Novo Nordisk Pk, DK-2760 Malov, Denmark
Novo Nordisk AS, Global Res, Novo Nordisk Pk, DK-2760 Malov, Denmark
Rahbek, Ulrik Lytt
.
TISSUE BARRIERS,
2016,
4
(02)
[4]
In vitro toxicity assessment of oral nanocarriers
[J].
Ciappellano, Silvia Gabriella
论文数:
0
引用数:
0
h-index:
0
机构:
ECAMRICERT SRL, ECSIN, Viale Porta Adige 45, I-45100 Rovigo, Italy
ECAMRICERT SRL, ECSIN, Viale Porta Adige 45, I-45100 Rovigo, Italy
Ciappellano, Silvia Gabriella
;
Tedesco, Erik
论文数:
0
引用数:
0
h-index:
0
机构:
ECAMRICERT SRL, ECSIN, Viale Porta Adige 45, I-45100 Rovigo, Italy
ECAMRICERT SRL, ECSIN, Viale Porta Adige 45, I-45100 Rovigo, Italy
Tedesco, Erik
;
Venturini, Marco
论文数:
0
引用数:
0
h-index:
0
机构:
ECAMRICERT SRL, ECSIN, Viale Porta Adige 45, I-45100 Rovigo, Italy
ECAMRICERT SRL, ECSIN, Viale Porta Adige 45, I-45100 Rovigo, Italy
Venturini, Marco
;
Benetti, Federico
论文数:
0
引用数:
0
h-index:
0
机构:
ECAMRICERT SRL, ECSIN, Viale Porta Adige 45, I-45100 Rovigo, Italy
ECAMRICERT SRL, ECSIN, Viale Porta Adige 45, I-45100 Rovigo, Italy
Benetti, Federico
.
ADVANCED DRUG DELIVERY REVIEWS,
2016,
106
:381
-401
[5]
NEW APPROACH FOR ORAL-ADMINISTRATION OF INSULIN WITH POLYALKYLCYANOACRYLATE NANOCAPSULES AS DRUG CARRIER
[J].
DAMGE, C
论文数:
0
引用数:
0
h-index:
0
机构:
UNIV PARIS 11, PHARM GALEN & BIOPHARM LAB, F-92290 CHATENAY MALABRY, FRANCE
UNIV PARIS 11, PHARM GALEN & BIOPHARM LAB, F-92290 CHATENAY MALABRY, FRANCE
DAMGE, C
;
论文数:
引用数:
h-index:
机构:
MICHEL, C
;
APRAHAMIAN, M
论文数:
0
引用数:
0
h-index:
0
机构:
UNIV PARIS 11, PHARM GALEN & BIOPHARM LAB, F-92290 CHATENAY MALABRY, FRANCE
UNIV PARIS 11, PHARM GALEN & BIOPHARM LAB, F-92290 CHATENAY MALABRY, FRANCE
APRAHAMIAN, M
;
论文数:
引用数:
h-index:
机构:
COUVREUR, P
.
DIABETES,
1988,
37
(02)
:246
-251
[6]
Design and Development of a Cyclic Decapeptide Scaffold with Suitable Properties for Bioavailability and Oral Exposure
[J].
Fouche, Marianne
论文数:
0
引用数:
0
h-index:
0
机构:
Novartis Inst BioMed Res, Global Discovery Chem Macrocycles, CH-4002 Basel, Switzerland
Novartis Inst BioMed Res, Global Discovery Chem Macrocycles, CH-4002 Basel, Switzerland
Fouche, Marianne
;
Schafer, Michael
论文数:
0
引用数:
0
h-index:
0
机构:
Novartis Inst BioMed Res, Global Discovery Chem CADD, CH-4002 Basel, Switzerland
Novartis Inst BioMed Res, Global Discovery Chem Macrocycles, CH-4002 Basel, Switzerland
Schafer, Michael
;
Berghausen, Jorg
论文数:
0
引用数:
0
h-index:
0
机构:
Novartis Inst BioMed Res, Metab & Pharmacokinet, CH-4002 Basel, Switzerland
Novartis Inst BioMed Res, Global Discovery Chem Macrocycles, CH-4002 Basel, Switzerland
Berghausen, Jorg
;
Desrayaud, Sandrine
论文数:
0
引用数:
0
h-index:
0
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Univ Bath, Dept Pharm & Pharmacol, Bath BA2 7AY, Avon, England
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