Planning actions in autism

被引：148

作者：

Fabbri-Destro, Maddalena ^{[1
,2
]}

Cattaneo, Luigi ^{[1
]}

Boria, Sonia ^{[1
]}

Rizzolatti, Giacomo ^{[1
]}

机构：

[1] Univ Parma, Dipartimento Neurosci, I-43100 Parma, Italy

[2] Univ Ferrara, Dipartimento Sci Biomed & Terapie Avanzate, I-44100 Ferrara, Italy

来源：

EXPERIMENTAL BRAIN RESEARCH | 2009年 / 192卷 / 03期

关键词：

Autism; Motor acts; Action planning; Mirror neuron system; MIRROR NEURON SYSTEM; SPECTRUM DISORDERS; CORTICAL ACTIVATION; IMITATION; CHILDREN; HYPOTHESIS; MOVEMENT; CORTEX;

D O I：

10.1007/s00221-008-1578-3

中图分类号：

Q189 [神经科学];

学科分类号：

071006 [神经生物学];

摘要：

It has been suggested that the deficit in understanding others' intention in autism depends on a malfunctioning of the mirror system. This malfunction could be due either to a deficit of the basic mirror mechanism or to a disorganization of chained action organization on which the mirror understanding of others' intention is based. Here we tested this last hypothesis investigating the kinematics of intentional actions. Children with autism and typically developing children (TD) were asked to execute two actions consisting each of three motor acts: the first was identical in both actions while the last varied for its difficulty. The result showed that, unlike in TD children, in children with autism the kinematics of the first motor act was not modulated by the task difficulty. This finding strongly supports the notion that children with autism have a deficit in chaining motor acts into a global action.

引用

页码：521 / 525

页数：5

共 23 条

[1]

[Anonymous], 27 ANN M SOC NEUR NE

[2]

BORIA S, 2008, WHAT WHY AUTIS UNPUB

[3]

Impairment of actions chains in autism and its possible role in intention understanding [J].

Cattaneo, Luigi ;

Fabbri-Destro, Maddalena ;

Boria, Sonia ;

Pieraccini, Cinzia ;

Monti, Annalisa ;

Cossu, Giuseppe ;

Rizzolatti, Giacomo .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2007, 104 (45) :17825-17830

[4]

Observation and execution of movement: similarities demonstrated by quantified electroencephalography [J].

Cochin, S ;

Barthelemy, C ;

Roux, S ;

Martineau, J .

EUROPEAN JOURNAL OF NEUROSCIENCE, 1999, 11 (05) :1839-1842

[5]

Understanding emotions in others: mirror neuron dysfunction in children with autism spectrum disorders [J].

Dapretto, M ;

Davies, MS ;

Pfeifer, JH ;

Scott, AA ;

Sigman, M ;

Bookheimer, SY ;

Iacoboni, M .

NATURE NEUROSCIENCE, 2006, 9 (01) :28-30

[6]

Parietal lobe: From action organization to intention understanding [J].

Fogassi, L ;

Ferrari, PF ;

Gesierich, B ;

Rozzi, S ;

Chersi, F ;

Rizzolatti, G .

SCIENCE, 2005, 308 (5722) :662-667

[7]

Fuster J.M., 2002, Cortex and Mind: Unifying Cognition

[8]

Anatomical differences in the mirror neuron system and social cognition network in autism [J].

Hadjikhani, Nouchine ;

Joseph, Robert M. ;

Snyder, Josh ;

Tager-Flusberg, Helen .

CEREBRAL CORTEX, 2006, 16 (09) :1276-1282

[9]

Imitation and action understanding in autistic spectrum disorders: How valid is the hypothesis of a deficit in the mirror neuron system? [J].

Hamilton, Antonia F. de C. ;

Brindley, Rachel M. ;

Frith, Uta .

NEUROPSYCHOLOGIA, 2007, 45 (08) :1859-1868

[10]

Activation of human primary motor cortex during action observation: A neuromagnetic study [J].

Hari, R ;

Forss, N ;

Avikainen, S ;

Kirveskari, E ;

Salenius, S ;

Rizzolatti, G .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (25) :15061-15065

← 1 2 3 →