Thrombelastographic evaluation of the influence of 2-RBC apheresis on donor's coagulation system

被引：9

作者：

Akay, Olga Meltem ^{[1
]}

Karagulle, Mustafa ^{[1
]}

Kus, Gokhan ^{[1
]}

Mutlu, Fezan Sahm ^{[2
]}

Gunduz, Eren ^{[1
]}

机构：

[1] Eskisehir Osmangazi Univ, Sch Med, Dept Hematol, TR-26480 Eskisehir, Turkey

[2] Eskisehir Osmangazi Univ, Sch Med, Dept Biostat, TR-26480 Eskisehir, Turkey

来源：

TRANSFUSION AND APHERESIS SCIENCE | 2013年 / 48卷 / 03期

关键词：

Apheresis; Donor; Coagulation system; BLOOD; HYPERCOAGULABILITY; THROMBOELASTOGRAPHY; PLATELETPHERESIS; SAFETY;

D O I：

10.1016/j.transci.2013.04.023

中图分类号：

R5 [内科学];

学科分类号：

100201 [内科学];

摘要：

Rotation thrombelastogram (ROTEM (R)/TEG (R)) assays allow rapid global assessment of hemostatic function using whole blood. Since published data about the effects of automated red cell collection on coagulation system are scarce, we aimed to investigate the effects of 2-RBC apheresis on donor's coagulation system using ROTEM (R) assays. In INTEM assay, CFT was significantly shortened 24 h after apheresis compared with baseline value (p < 0.05) and MCF was significantly prolonged immediately after apheresis and 24 h after apheresis compared with baseline value (p <0.05 and p < 0.01, respectively). In EXTEM assay, CFT was significantly prolonged immediately after apheresis and 24 h after apheresis compared with baseline value (p = 0.001 and p < 0.001, respectively) and MCF was significantly prolonged 24 h after apheresis compared with baseline value (p < 0,001). Our results demonstrate thromboelastographic signs of hypercoagulability in donors undergoing 2-RBC apheresis. (C) 2013 Elsevier Ltd. All rights reserved.

引用

页码：387 / 390

页数：4

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