Unique and efficient synthesis of [2S-(2R,3S,4R*)]-2-amino-1-cyclohexyl-6-methyl-3,4-heptanediol, a popular C-terminal component of many renin inhibitors

被引：39

作者：

Schwindt, MA

Belmont, DT

Carlson, M

Franklin, LC

Hendrickson, VS

Karrick, GL

Poe, RW

Sobieray, DM

VandeVusse, J

机构：

[1] Chemical Development Department, Parke-Davis Pharmaceutical Res. Div., Holland, MI 49424

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1996年 / 61卷 / 26期

关键词：

D O I：

10.1021/jo960694n

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[No abstract available]

引用

页码：9564 / 9568

页数：5

共 33 条

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[2] A PRACTICAL SYNTHESIS OF THE DIHYDROXYETHYLENE DIPEPTIDE ISOSTERE, (2S,3R,4S) 2-[(TERT-BUTYLOXYCARBONYL)AMINO]-1-CYCLOHEXYL-3,4-DIHYDROXY-6-METHYLHEPTANE, FROM D-ISOASCORBIC ACID
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[3] A VERSATILE AND STEREOSPECIFIC SYNTHESIS OF A DIHYDROXYETHYLENE DIPEPTIDE ISOSTERE OF RENIN INHIBITORS FROM D-RIBOSE
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[10] TANDEM ORGANOMETALLIC ADDITION-REACTIONS TO N-METHOXY-UREAS AND URETHANES IN THE PREPARATION OF UNSYMMETRICAL AND SYMMETRICAL KETONES
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Unique and efficient synthesis of [2S-(2R*,3S*,4R*)]-2-amino-1-cyclohexyl-6-methyl-3,4-heptanediol, a popular C-terminal component of many renin inhibitors

Unique and efficient synthesis of [2S-(2R,3S,4R*)]-2-amino-1-cyclohexyl-6-methyl-3,4-heptanediol, a popular C-terminal component of many renin inhibitors