Heterogeneous Henry reaction of aldehydes: Diastereoselective synthesis of nitroalcohol derivatives over Mg-Al hydrotalcites.

被引：89

作者：

Bulbule, VJ ^{[1
]}

Deshpande, VH ^{[1
]}

Velu, S ^{[1
]}

Sudalai, A ^{[1
]}

Sivasankar, S ^{[1
]}

Sathe, VT ^{[1
]}

机构：

[1] Natl Chem Lab, Pune 41100, Maharashtra, India

来源：

TETRAHEDRON | 1999年 / 55卷 / 30期

关键词：

aldols; diastereoselection; catalysts; aldehydes;

D O I：

10.1016/S0040-4020(99)00494-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Mg-Al Hydrotalcite (HT) has been found to catalyze the reaction between aldehydes and nitroalkanes very efficiently affording three nitroalkanols in a highly diastereoselective manner. The ratios of threolerythro isomers are determined from their respective C-13-NMR spectra. A mechanism based on the transition state model for the predominant formation of threo-isomers is also described. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：9325 / 9332

页数：8

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