Nanoscopic Porous Sensors

被引:245
作者
Kasianowicz, John J. [1 ]
Robertson, Joseph W. F. [1 ]
Chan, Elaine R. [1 ]
Reiner, Joseph E. [1 ]
Stanford, Vincent M. [2 ]
机构
[1] Natl Inst Stand & Technol, Div Semicond Elect, Elect & Elect Engn Lab, Gaithersburg, MD 20899 USA
[2] Natl Inst Stand & Technol, Informat Access Div, Informat Technol Lab, Gaithersburg, MD 20899 USA
关键词
analyte detection; Coulter counter; DNA sequencing; ion channel; nanopore-based sensor; resistive-pulse detection;
D O I
10.1146/annurev.anchem.1.031207.112818
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
There are thousands of different nanometer-scale pores in biology, many of which act as sensors for specific chemical agents. Recent work suggests that protein and solid-state nanopores have many potential uses in a wide variety of analytical applications. In this review we survey this field of research and discuss the prospects for advances that could he made in the near future.
引用
收藏
页码:737 / 766
页数:30
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