Rapid Fabrication of Complex 3D Extracellular Microenvironments by Dynamic Optical Projection Stereolithography

被引：354

作者：

Zhang, A. Ping ^{[1
,2
]}

Qu, Xin ^{[1
]}

Soman, Pranav ^{[1
]}

Hribar, Kolin C. ^{[1
]}

Lee, Jin W. ^{[1
]}

Chen, Shaochen ^{[1
]}

He, Sailing ^{[2
]}

机构：

[1] Univ Calif San Diego, Dept NanoEngn, San Diego, CA 92093 USA

[2] Zhejiang Univ, Ctr Opt & Electromagnet Res, State Key Lab Modern Opt Instrumentat, Hangzhou 310058, Zhejiang, Peoples R China

来源：

ADVANCED MATERIALS | 2012年 / 24卷 / 31期

基金：

美国国家科学基金会; 中国国家自然科学基金;

关键词：

extracelluar microenviroment; cell culture; soft material; optical projection stereolithography; maskless lithography; TISSUE ENGINEERING SCAFFOLDS; CELL-CULTURE; TOPOGRAPHY; MECHANOTRANSDUCTION; MICROFABRICATION; PATTERNS; GROWTH; FORM;

D O I：

10.1002/adma.201202024

中图分类号：

O6 [化学];

学科分类号：

070301 [无机化学];

摘要：

The topographic features of the extracelluar matrix (ECM) lay the foundation for cellular behavior. A novel biofabrication method using a digitalmirror device (DMD), called dynamic optical projection stereolithography (DOPsL) is demonstrated. This robust and versatile platform can generate complex biomimetic scaffolds within seconds. Such 3D scaffolds have promising potentials for studying cell interactions with microenvironments in vitro and in vivo.

引用

收藏

页码：4266 / +

页数：6

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