共 31 条
Effects of rTMS on an auditory oddball task: a pilot study of cortical plasticity and the EEG
被引:15
作者:
Cooper, N. R.
[1
]
Fitzgerald, P. B.
[1
]
Croft, R. J.
[2
]
Upton, D. J.
[1
]
Segrave, R. A.
[1
]
Daskalakis, Z. J.
[3
]
Kulkarni, J.
[1
]
机构:
[1] Monash Univ, Alfred Psychiat Res Ctr, Dept Psychol Med, Melbourne, Vic 3004, Australia
[2] Swinburne Univ Technol, Brain Sci Inst, Hawthorn, Vic 3122, Australia
[3] Univ Toronto, Dept Psychiat, Ctr Addict & Mental Hlth, Toronto, ON M5S 1A1, Canada
基金:
澳大利亚国家健康与医学研究理事会;
关键词:
depression;
electroencephaolgraphy;
P300;
transcranial magnetic stimulation;
D O I:
10.1177/155005940803900308
中图分类号:
R74 [神经病学与精神病学];
学科分类号:
摘要:
The objective of this study was to explore the effects of 1Hz repetitive transcranial magnetic stimulation (rTMS) applied to dorsal lateral prefrontal cortex (DLPFC) on both an EEG index of cortical excitation and inhibition, event-related desynchronization/ synchronization (ERD/S) and on the P300 component of an auditory oddball-induced ERP. Eight normal participants received 15 minutes of 1Hz rTMS at 110% of the resting motor threshold to right DLPFC. ERD/S of alpha and beta bands was measured during an auditory oddball task immediately before and after stimulation. There was significantly less alpha desynchronization post-TMS, and this effect was widespread excepting posterior midline sites. No changes were found to oddball-P300 amplitudes or latencies. In conclusion, the findings of less alpha desynchronization post-TMS are compatible with notions of slow rTMS causing a decrease in cortical excitation.
引用
收藏
页码:139 / 143
页数:5
相关论文

