RETRACTED: Immunosuppressive networks in the tumour environment and their effect in dendritic cells (Retracted article. See vol. 1835, pg. 259, 2013)

被引：32

作者：

Bennaceur, Karim ^{[1
]}

Chapman, Jessica Alice ^{[3
]}

Touraine, Jean-louis ^{[1
,2
]}

Portoukalian, Jacques ^{[2
]}

机构：

[1] Univ Lyon 1, Dept Transplantat & Clin Immunol, F-69365 Lyon, France

[2] Univ Lyon 1, Hop Edouard Herriot, Dept R, Lab Dermatol Res,EA 41 69, F-69437 Lyon 03, France

[3] Univ Manchester, Fac Life Sci, Manchester M13 9PL, Lancs, England

来源：

BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER | 2009年 / 1795卷 / 01期

关键词：

Tumour escape; Dendritic cell; immune dysfunction; Tumour microenvironment; ENDOTHELIAL GROWTH-FACTOR; ANTIGEN-PRESENTING FUNCTION; COLONY-STIMULATING FACTOR; T-CELL; MULTIPLE-MYELOMA; IMMUNE-RESPONSE; MALIGNANT-MELANOMA; LANGERHANS CELLS; NATURAL-KILLER; JANUS KINASES;

D O I：

10.1016/j.bbcan.2008.07.001

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The failure of the immune system to provide protection against turnout cells is an important immunological problem. It is now evident that inadequate function of the host immune system is one of the main mechanisms by which tumours escape from immune control, as well as an important factor that limits the success of cancer immunotherapy. In recent years, it has become increasingly clear that defects in dendritic cells have a crucial role in non-responsiveness to tumours. This article focuses on the functional consequences and recently described mechanisms of the dendritic-cell defects in cancer. (C) 2008 Elsevier B.V. All rights reserved.

引用

页码：16 / 24

页数：9

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