The biotechnological potential and design of novel carotenoids by gene combination in Escherichia coli

被引：85

作者：

Sandmann, G

Albrecht, M

Schnurr, G

Knörzer, O

Böger, P

机构：

[1] Goethe Univ Frankfurt, Biosynthesis Grp, Inst Bot, D-60054 Frankfurt, Germany

[2] Univ Konstanz, Lehrstuhl Physiol & Biochem & Pflanzen, D-78434 Constance, Germany

来源：

TRENDS IN BIOTECHNOLOGY | 1999年 / 17卷 / 06期

关键词：

D O I：

10.1016/S0167-7799(99)01307-4

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Carotenoids are antioxidants with considerable pharmaceutical potential. More than 600 carotenoid structures are known but their availability is limited owing to practical difficulties associated with chemical synthesis and isolation from microorganisms or plant tissue. To overcome some of these problems, heterologous expression of carotenoid genes in Escherichia coli can be used for the synthesis of rare derivatives or even of novel carotenoids. Novel and rare carotenoids can be obtained by combining carotenoid genes from different host species in E. coli.

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页码：233 / 237

页数：5

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