De Testimonio: on the evidence for decisions about the use of therapeutic interventions

被引：64

作者：

Rawlins, Michael ^{[1
,2
]}

机构：

[1] Natl Inst Hlth & Clin Excellence, London WC1V 6NA, England

[2] Newcastle Univ, Newcastle Upon Tyne NE1 7RU, Tyne & Wear, England

来源：

CLINICAL MEDICINE | 2008年 / 8卷 / 06期

关键词：

case-control studies; hierarchies of evidence; historical controlled trials; randomised controlled trials;

D O I：

10.7861/clinmedicine.8-6-579

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Decisions about the use of therapeutic interventions, whether for individuals or entire healthcare systems, should be based on the totality of the available evidence. The notion that evidence can be reliably or usefully placed in 'hierarchies' is illusory. Rather, decision makers need to exercise judgement about whether (and when) evidence gathered from experimental or observational sources is fit for purpose.

引用

页码：579 / 588

页数：10

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