A formal synthesis of castanospermine using an olefin metathesis cyclisation reaction as a key step

被引：99

作者：

Overkleeft, HS ^{[1
]}

Pandit, UK ^{[1
]}

机构：

[1] UNIV AMSTERDAM,ORGAN CHEM LAB,1018 WS AMSTERDAM,NETHERLANDS

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 04期

关键词：

D O I：

10.1016/0040-4039(95)02237-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The formal synthesis of castanospermine (1) starting from tetrabenylgluconolactam (3) is described. Olefin metathesis cyclisation reaction of dialkene 9, derived from 3, leads to indolizidinone 10, which can be used as a key intermediate for the synthesis of castanospermine (1) and its analogues.

引用

页码：547 / 550

页数：4

共 24 条

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