A NOVEL-APPROACH TO AZASUGARS FROM VINYL GLYCINE METHYL-ESTER VIA OLEFIN METATHESIS

被引：88

作者：

HUWE, CM ^{[1
]}

BLECHERT, S ^{[1
]}

机构：

[1] TECH UNIV BERLIN,INST ORGAN CHEM,D-10623 BERLIN,GERMANY

来源：

TETRAHEDRON LETTERS | 1995年 / 36卷 / 10期

关键词：

D O I：

10.1016/0040-4039(94)02308-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel strategy for the synthesis of azasugars from vinyl glycine methyl ester was designed, using an olefin metathesis as a key step. As a first test of this strategy, rac-trans-2-hydroxymethyl-3-hydroxypyrrolidine, which was isolated as the (2R,3S)-isomer from the legume Castanospermum australe, was synthesized.

引用

页码：1621 / 1624

页数：4

共 12 条

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