Determination of active ingredients in the pharmaceutical formulations containing hydrochlorothiazide and its binary mixtures with benazepril hydrochloride, triamterene and cilazapril by ratio spectra derivative spectrophotometry and vierordt's method

被引：53

作者：

Erk, N ^{[1
]}

机构：

[1] Ankara Univ, Fac Pharm, Dept Analyt Chem, TR-06100 Ankara, Turkey

来源：

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS | 1999年 / 20卷 / 1-2期

关键词：

hydrochlorothiazide; benazepril hydrochloride; triamterene; cilazapril; simultaneous determination; pharmaceutical preparations; ratio spectra derivative spectrophotometry; Vierordt's method;

D O I：

10.1016/S0731-7085(99)00009-6

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Procedures were developed for the simultaneous determination of pharmaceuticals in binary mixtures, containing hydrochlorothiazide-benazepril hydrochloride, hydrochlorothiazide-triamterene and hydrochlorothiazide-cilazapril by ratio spectra derivative spectrophotometry and Vierordt's method. Mean recoveries, relative standard deviations and linearity ranges in calibration graphs of the methods were compared. These procedures were successfully applied to three pharmaceutical formulations for the determination of active ingredients. (C) 1999 Elsevier Science B.V. All rights reserved.

引用

页码：155 / 167

页数：13

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