学术探索
学术期刊
新闻热点
数据分析
智能评审

The SREBP pathway: Regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor

被引：3039
作者：
Brown, MS
Goldstein, JL
机构：
[1] Department of Molecular Genetics, University of Texas, Southwestern Medical Center, Dallas
来源：
CELL | 1997年 / 89卷 / 03期
关键词：
D O I：
10.1016/S0092-8674(00)80213-5
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
[No abstract available]
引用
收藏
页码：331 / 340
页数：10
相关论文
共 62 条
  • [41] Cholesterol modification of hedgehog signaling proteins in animal development
    Porter, JA
    Young, KE
    Beachy, PA
    [J]. SCIENCE, 1996, 274 (5285) : 255 - 259
  • [42] Sterol-regulated release of SREBP-2 from cell membranes requires two sequential cleavages, one within a transmembrane segment
    Sakai, J
    Duncan, EA
    Rawson, RB
    Hua, XX
    Brown, RS
    Goldstein, JL
    [J]. CELL, 1996, 85 (07) : 1037 - 1046
  • [43] SATO R, 1994, J BIOL CHEM, V269, P17267
  • [44] Schoenheimer R, 1933, J BIOL CHEM, V103, P439
  • [45] Amyloid beta-protein and the genetics of Alzheimer's disease
    Selkoe, DJ
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1996, 271 (31) : 18295 - 18298
  • [46] INDEPENDENT REGULATION OF STEROL REGULATORY ELEMENT-BINDING PROTEIN-1 AND PROTEIN-2 IN HAMSTER LIVER
    SHENG, ZQ
    OTANI, H
    BROWN, MS
    GOLDSTEIN, JL
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1995, 92 (04) : 935 - 938
  • [47] Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a
    Shimano, H
    Horton, JD
    Hammer, RE
    Shimomura, I
    Brown, MS
    Goldstein, JL
    [J]. JOURNAL OF CLINICAL INVESTIGATION, 1996, 98 (07) : 1575 - 1584
  • [48] Isoform 1c of sterol regulatory element binding protein is less active than isoform 1a in livers of transgenic mice and in cultured cells
    Shimano, H
    Horton, JD
    Shimomura, I
    Hammer, RE
    Brown, MS
    Goldstein, JL
    [J]. JOURNAL OF CLINICAL INVESTIGATION, 1997, 99 (05) : 846 - 854
  • [49] Differential expression of exons 1a and 1c in mRNAs for sterol regulatory element binding protein-1 in human and mouse organs and cultured cells
    Shimomura, I
    Shimano, H
    Horton, JD
    Goldstein, JL
    Brown, MS
    [J]. JOURNAL OF CLINICAL INVESTIGATION, 1997, 99 (05) : 838 - 845
  • [50] SIPERSTEIN MD, 1966, J BIOL CHEM, V241, P602
1234567