From computer simulations to human disease: Emerging themes in protein folding

被引：102

作者：

Radford, SE ^{[1
]}

Dobson, CM

机构：

[1] Univ Leeds, Sch Biochem & Mol Biol, Leeds LS2 9JT, W Yorkshire, England

[2] Univ Oxford, Oxford Ctr Mol Sci, New Chem Lab, Oxford OX1 3QT, England

来源：

CELL | 1999年 / 97卷 / 03期

关键词：

D O I：

10.1016/S0092-8674(00)80739-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：291 / 298

页数：8

共 43 条

[1] PRINCIPLES THAT GOVERN FOLDING OF PROTEIN CHAINS [J].

ANFINSEN, CB .

SCIENCE, 1973, 181 (4096) :223-230

[2] Formation and stability of β-hairpin structures in polypeptides [J].

Blanco, F ;

Ramírez-Alvarado, M ;

Serrano, L .

CURRENT OPINION IN STRUCTURAL BIOLOGY, 1998, 8 (01) :107-111

[3] FUNNELS, PATHWAYS, AND THE ENERGY LANDSCAPE OF PROTEIN-FOLDING - A SYNTHESIS [J].

BRYNGELSON, JD ;

ONUCHIC, JN ;

SOCCI, ND ;

WOLYNES, PG .

PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 1995, 21 (03) :167-195

[4] The Hsp70 and Hsp60 chaperone machines [J].

Bukau, B ;

Horwich, AL .

CELL, 1998, 92 (03) :351-366

[5] Thermodynamic stability of wild-type and mutant p53 core domain [J].

Bullock, AN ;

Henckel, J ;

DeDecker, BS ;

Johnson, CM ;

Nikolova, PV ;

Proctor, MR ;

Lane, DP ;

Fersht, AR .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1997, 94 (26) :14338-14342

[6] The energy landscape of a fast-folding protein mapped by Ala->Gly substitutions [J].

Burton, RE ;

Huang, GS ;

Daugherty, MA ;

Calderone, TL ;

Oas, TG .

NATURE STRUCTURAL BIOLOGY, 1997, 4 (04) :305-310

[7] The Greek key protein apo-pseudoazurin folds through an obligate on-pathway intermediate [J].

Capaldi, AP ;

Ferguson, SJ ;

Radford, SE .

JOURNAL OF MOLECULAR BIOLOGY, 1999, 286 (05) :1621-1632

[8] Kinetic studies of β-sheet protein folding [J].

Capaldi, AP ;

Radford, SE .

CURRENT OPINION IN STRUCTURAL BIOLOGY, 1998, 8 (01) :86-92

[9] Submillisecond protein folding kinetics studied by ultrarapid mixing [J].

Chan, CK ;

Hu, Y ;

Takahashi, S ;

Rousseau, DL ;

Eaton, WA ;

Hofrichter, J .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1997, 94 (05) :1779-1784

[10] Designing conditions for in vitro formation of amyloid protofilaments and fibrils [J].

Chiti, F ;

Webster, P ;

Taddei, N ;

Clark, A ;

Stefani, M ;

Ramponi, G ;

Dobson, CM .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (07) :3590-3594

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