Microfluidic technology for assisted reproduction

被引：112

作者：

Beebe, D ^{[1
]}

Wheeler, M

Zeringue, H

Walters, E

Raty, S

机构：

[1] Univ Wisconsin, Dept Biomed Engn, Madison, WI 53706 USA

[2] Univ Illinois, Dept Anim Sci, Urbana, IL 61801 USA

来源：

THERIOGENOLOGY | 2002年 / 57卷 / 01期

关键词：

microfluidic; embryo; culture; maturation; livestock; bovine; in vitro production;

D O I：

10.1016/S0093-691X(01)00662-8

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The physical tools used in assisted reproduction have changed little over several decades. Microfluidics is an emerging technology that allows a fresh examination of the way assisted reproduction is performed. Here we review our work to develop microfluidic devices to perform the functions required in assisted reproduction. These functions include loading/unloading, culture, chemical manipulation, and mechanical manipulation of embryos and oocytes. Basic microfluidic theory and microfluidic device design and operation are discussed. Results are presented for mechanical removal of cumulus cells and for embryo culture, Results suggest that microfluidic systems will lead to improved efficiencies in assisted reproduction. (C) 2001 by Elsevier Science Inc.

引用

页码：125 / 135

页数：11

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