Hepatic lesion detection at MR imaging: A comparative study with four sequences

被引：61

作者：

Blakeborough, A ^{[1
]}

Ward, J ^{[1
]}

Wilson, D ^{[1
]}

Griffiths, M ^{[1
]}

Kajiya, Y ^{[1
]}

Guthrie, JA ^{[1
]}

Robinson, PJA ^{[1
]}

机构：

[1] ST JAMES UNIV HOSP,DEPT RADIOL,MAGNET RESONANCE IMAGING UNIT,LEEDS LS9 7TF,W YORKSHIRE,ENGLAND

来源：

RADIOLOGY | 1997年 / 203卷 / 03期

关键词：

gadolinium; ion; liver neoplasms; MR; magnetic resonance (MR); contrast enhancement; pulse sequences; receiver operating characteristic curve (ROC);

D O I：

10.1148/radiology.203.3.9169701

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

PURPOSE: To compare results with the following magnetic resonance (MR) imaging sequences in the detection of focal hepatic lesions: fast spin-echo (SE) before and after administration of superparamagnetic iron oxide (SPIO) particles, fat-suppressed T2-weighted SE, and dynamic gadolinium-enhanced fast low-angle shot (FLASH). MATERIALS AND METHODS: In 26 patients with known malignancy and documented focal liver lesions, 1.0-T MR imaging was performed prior to hepatic resection. All images were reviewed independently by four blinded observers. Sensitivity was calculated for each sequence and for each observer by means of alternative-free-response receiver operating characteristic (ROC) methods. RESULTS: The mean area under the alternative-free-response ROC curve with SPIO-enhanced fast SE (0.85) was significantly greater (P < .02) than that with all other Sequences. Detection was significantly improved with SPIO-enhanced fast SE compared with dynamic gadolinium-enhanced FLASH (which was the best of the other three sequences) for all lesions (P < .002) and for malignant lesions (P < .0002). CONCLUSION Findings with the SPIO-enhanced fast SE sequence improved detection of focal liver lesions and had the highest diagnostic accuracy.

引用

页码：759 / 765

页数：7