Surface design of core-shell superparamagnetic iron oxide nanoparticles drives record relaxivity values in functional MRI contrast agents

被引：42

作者：

Maity, Dipak ^{[1
]}

Zoppellaro, Giorgio ^{[1
]}

Sedenkova, Veronika ^{[1
]}

Tucek, Jiri ^{[1
]}

Safarova, Klara ^{[1
]}

Polakova, Katerina ^{[1
]}

Tomankova, Katerina ^{[1
,2
]}

Diwoky, Clemens ^{[3
]}

Stollberger, Rudolf ^{[3
]}

Machala, Libor ^{[1
]}

Zboril, Radek ^{[1
]}

机构：

[1] Palacky Univ, Reg Ctr Adv Technol & Mat, Olomouc 77146, Czech Republic

[2] Palacky Univ, Fac Med & Dent, Olomouc 77146, Czech Republic

[3] Graz Univ Technol, Inst Med Engn, A-8010 Graz, Austria

来源：

CHEMICAL COMMUNICATIONS | 2012年 / 48卷 / 93期

关键词：

ONE-POT REACTION; MAGNETITE NANOPARTICLES; STABILIZATION; NANOCRYSTALS;

D O I：

10.1039/c2cc35515a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Core-shell hydrophilic superparamagnetic iron oxide (SPIO) nanoparticles, surface functionalized with either terephthalic acid or 2-amino terephthalic acid, showed large negative MRI contrast ability, validating the advantage of using low molecular weight and pi-conjugated canopies for engineering functional nanostructures with superior performances.

引用

页码：11398 / 11400

页数：3

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