Metallation in connection with cross-coupling reactions. Coupling of hindered aryls for the synthesis of 4-phenylpyridines as part of Streptonigrin and Lavendamycin analogues

被引：24

作者：

Godard, A ^{[1
]}

Rocca, P ^{[1
]}

Pomel, V ^{[1
]}

ThomasditDumont, L ^{[1
]}

Rovera, JC ^{[1
]}

Thaburet, JF ^{[1
]}

Marsais, F ^{[1
]}

Queguiner, G ^{[1
]}

机构：

[1] INST NATL SCI APPL ROUEN,IRCOF,LAB CHIM ORGAN FINE & HETEROCYCLIQUE,URA 1429,F-76131 MONT ST AIGNAN,FRANCE

来源：

JOURNAL OF ORGANOMETALLIC CHEMISTRY | 1996年 / 517卷 / 1-2期

关键词：

palladium; orthometallation; synthesis; 4-phenylpyridines;

D O I：

10.1016/0022-328X(95)05979-Y

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The synthesis of the C-D ring system of Streptonigrin and Lavendamycin alkaloid analogues by cross-coupling under Suzuki's conditions has been studied. Steric hindrance is the main problem. It has been solved either by using strong bases or working in a sealed tube under pressure.

引用

页码：25 / 36

页数：12

共 14 条

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