Ultrasound Contrast Agents: Updated Data on Safety Profile

被引：6

作者：

Aggeli, C. ^{[1
]}

Felekos, I. ^{[1
]}

Siasos, G. ^{[1
]}

Tousoulis, D. ^{[1
]}

Stefanadis, C. ^{[1
]}

机构：

[1] Univ Athens, Sch Med, Dept Cardiol 1, Hippokrat Hosp, GR-11527 Athens, Greece

来源：

CURRENT PHARMACEUTICAL DESIGN | 2012年 / 18卷 / 15期

关键词：

Contrast echocardiography; safety; PREMATURE VENTRICULAR CONTRACTIONS; ACTIVATION-RELATED PSEUDOALLERGY; STRESS ECHOCARDIOGRAPHY; CLINICAL-APPLICATIONS; MYOCARDIAL-PERFUSION; SYSTOLIC PRESSURE; RECOMMENDATIONS; OPTISON; DRUG;

D O I：

10.2174/138161212800099964

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Contrast echocardiography represents a major technological advancement in the constantly evolving field of cardiovascular imaging. Over the last twenty years numerous studies have been published, illustrating the incremental value of contrast implementation into a variety of clinical scenarios. However, serious concerns have been raised about contrast safety profile, mainly based on post-marketing observational data and several animal studies. The latter have investigated contrast bio effects under experimental conditions that are not consistent with daily clinical practice. On the other hand, numerous clinical trials with large registries have proven otherwise. Not only contrast agents are efficient, but they also demonstrate a remarkable safety profile. So the question is: should we fear contrast utilization or should we consider them as an adjunctive and indispensable clinical tool for daily bedside practice?

引用

页码：2253 / 2258

页数：6

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