Nuclear organization and gene expression: Homologous pairing and long-range interactions

被引:79
作者
Henikoff, S
机构
[1] Howard Hughes Medical Institute, Basic Sciences Division, Fred Hutchinson Cancer Res. Center, Seattle
关键词
D O I
10.1016/S0955-0674(97)80012-9
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Genetic studies have demonstrated that pairing interactions between homologous chromosomes and long-range associations between nonhomologous sites can influence gene expression. Recent work has revealed that such influences are widespread in eukaryotes and that chromosome architecture is likely to be of fundamental importance for nuclear structure and function.
引用
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页码:388 / 395
页数:8
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