An aerobic ligandless palladium acetate catalysed Suzuki-Miyaura cross-coupling reaction in an aqueous solvent

被引：11

作者：

Li, Chen ^{[1
,2
]}

Li, Xiao-Qiang ^{[1
]}

Zhang, Chi ^{[1
]}

机构：

[1] Nankai Univ, State Key Lab Elementoorgan Chem, Tianjin 300071, Peoples R China

[2] CNOOC, Key Lab Catalyt Technol, Tianjin Chem Res & Design Inst, Tianjin, Peoples R China

来源：

JOURNAL OF CHEMICAL RESEARCH-S | 2008年 / 09期

基金：

中国国家自然科学基金;

关键词：

Suzuki-Miyaura reaction; ligandless; palladium acetate; aqueous solvent;

D O I：

10.3184/030823408X349952

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The Suzuki-Miyaura reaction of aryl iodides and aryl bromides was catalysed by Pd(OAc)(2) (1 mol%) using K3PO4 center dot 3H(2)O (2 equiv) as base in dimethyl acetamide DMA-H2O (1: 1) at room temperature. Changes in the loading of Pd(OAc)2 (from 1 mol% to 2 mol%), temperature (from room temperature to 80 degrees C) and the ratio of DMA to water (from 1: 1 to 5: 1) resulted in the successful coupling of activated aryl chlorides with phenylboronic acid.

引用

页码：525 / 527

页数：3

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