Pertussis serostatus among neonates born to hispanic women

被引：31

作者：

Healy, CM

Rench, MA

Edwards, KM

Baker, CJ

机构：

[1] Baylor Coll Med, Dept Pediat, Infect Dis Sect, Houston, TX 77030 USA

[2] Baylor Coll Med, Dept Mol Virol & Microbiol, Infect Dis Sect, Houston, TX 77030 USA

[3] Ben Taub Gen Hosp, Houston, TX 77030 USA

[4] Vanderbilt Univ, Sch Med, Dept Pediat, Div Infect Dis, Nashville, TN 37212 USA

来源：

CLINICAL INFECTIOUS DISEASES | 2006年 / 42卷 / 10期

关键词：

D O I：

10.1086/503567

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The reasons for the higher pertussis incidence among Hispanic infants, compared with among infants of other ethnicities, are unknown. The geometric mean concentration of pertussis toxin-specific immunoglobulin G in serum samples from 220 Hispanic neonates was 8.45 EU/mL, as determined by enzyme-linked immunosorbent assay, and it was significantly lower if mothers were adolescents (4.63 EU/ mL; P <= .001). A lack of maternal immunity is one explanation for pertussis susceptibility in very young Hispanic infants.

引用

收藏

页码：1439 / 1442

页数：4

相关论文

共 18 条

[1] Infant pertussis - Who was the source? [J].

Bisgard, KM ;

Pascual, FB ;

Ehresmann, KR ;

Miller, CA ;

Cianfrini, C ;

Jennings, CE ;

Rebmann, CA ;

Gabel, J ;

Schauer, SL ;

Lett, SM .

PEDIATRIC INFECTIOUS DISEASE JOURNAL, 2004, 23 (11) :985-989

[2] The seroepidemiology of Bordetella pertussis infections: A study of persons ages 1-65 years [J].

Cattaneo, LA ;

Reed, GW ;

Haase, DH ;

Wills, MJ ;

Edwards, KM .

JOURNAL OF INFECTIOUS DISEASES, 1996, 173 (05) :1256-1259

[3]

*CDCP, 2002, MMWR-MORBID MORTAL W, V51, P73

[4] Pertussis: an important target for maternal immunization [J].

Edwards, KM .

VACCINE, 2003, 21 (24) :3483-3486

[5]

ENGLUND JA, 1995, PEDIATRICS, V96, P580

[6]

Groseclose Samuel L, 2004, MMWR Morb Mortal Wkly Rep, V51, P1

[7] Prevalence of pertussis antibodies in maternal delivery, cord, and infant serum [J].

Healy, CM ;

Munoz, FM ;

Rench, MA ;

Halasa, NB ;

Edwards, KM ;

Baker, CJ .

JOURNAL OF INFECTIOUS DISEASES, 2004, 190 (02) :335-340

[8] Crucial role of antibodies to pertactin in Bordetella pertussis immunity [J].

Hellwig, SMM ;

Rodriguez, ME ;

Berbers, GAM ;

de Winkel, JGJV ;

Mooi, FR .

JOURNAL OF INFECTIOUS DISEASES, 2003, 188 (05) :738-742

[9] Risk factors for pertussis in young infants during an outbreak in Chicago in 1993 [J].

Izurieta, HS ;

Kenyon, TA ;

Strebel, PM ;

Baughman, AL ;

Shulman, ST ;

Wharton, M .

CLINICAL INFECTIOUS DISEASES, 1996, 22 (03) :503-507

[10] Immune responses and antibody decay after immunization of adolescents and adults with an acellular pertussis vaccine: The APERT study [J].

Le, T ;

Cherry, JD ;

Chang, SJ ;

Knoll, MD ;

Lee, ML ;

Barenkamp, S ;

Bernstein, D ;

Edelman, R ;

Edwards, KM ;

Greenberg, D ;

Keitel, W ;

Treanor, J ;

Ward, JI .

JOURNAL OF INFECTIOUS DISEASES, 2004, 190 (03) :535-544