(R)-(+) and (S)-(-) ethyl 4,4,4-trifluoro-3-hydroxy butanoate by enantioselective Baker's yeast reduction

被引：29

作者：

Davoli, P ^{[1
]}

Forni, A ^{[1
]}

Moretti, I ^{[1
]}

Prati, F ^{[1
]}

Torre, G ^{[1
]}

机构：

[1] Univ Modena, Dipartimento Chim, I-41100 Modena, Italy

来源：

ENZYME AND MICROBIAL TECHNOLOGY | 1999年 / 25卷 / 1-2期

关键词：

yeast reduction; enzyme inhibitor; allyl bromide; allyl alcohol; (R)-(+) and (S)-(-) ethyl 4,4,4-trifluoro-3-hydroxybutanoate;

D O I：

10.1016/S0141-0229(99)00025-3

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

(R)-(+) and (S)-(-) ethyl 4,4,4-trifluoro-3-hydroxybutanoate are obtained both by enantioselective Baker's yeast reduction of ethyl 4,4,4-trifluoro-3-oxobutanoate in the presence of allyl bromide or allyl alcohol. The two additives act as inhibitors of Si or Re yeast-enzymes, respectively. (C) 1999 Elsevier Science Inc. All rights reserved.

引用

页码：149 / 152

页数：4

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[2]

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